Related Experiment Video
Updated: Jul 2, 2025

10:24
Next-generation Sequencing of 16S Ribosomal RNA Gene Amplicons
Published on: August 29, 2014
83.5K
Detection of invasive Bartonella infections with next-generation sequencing of microbial cell-free DNA
Fernando H Centeno1, Ahmed M Hamdi1,2, Todd M Lasco3,2
1Department of Medicine, Baylor College of Medicine, Houston, TX, USA.
Antimicrobial Stewardship & Healthcare Epidemiology : ASHE
|February 28, 2024
Abstract:
We report 9 patients with invasive Bartonella infections, including 5 with endocarditis, who were diagnosed with microbial cell-free DNA next-generation sequencing and Bartonella serology studies. Diagnosis with plasma mcfDNA NGS enabled a faster clinical and laboratory diagnosis in 8 patients. Prompt diagnosis impacted antibiotic management in all 9 patients.

