Related Experiment Video
Updated: Jul 2, 2025
Multi-Modal Home Sleep Monitoring in Older Adults
Published on: January 26, 2019
Long-term night-to-night variability of sleep-disordered breathing using a radar-based home sleep apnea test: a
Samuel Tschopp1,2, Urs Borner1, Marco Caversaccio1
1Department of Otorhinolaryngology, Head and Neck Surgery, Inselspital, University Hospital and University of Bern, Bern, Switzerland.
Study Objectives:
Night-to-night variability of sleep-disordered breathing limits the diagnostic accuracy of a single measurement. Multiple recordings using a reliable, affordable method could reduce the uncertainty and avoid misdiagnosis, which could be possible with radar-based home sleep apnea testing (HSAT).
Methods:
We recruited consecutive patients with suspected sleep-disordered breathing and performed contactless radar-based HSAT with automated scoring (Sleepiz One; Sleepiz AG, Zurich, Switzerland) over 10 nights. During the first night, patients were simultaneously measured with peripheral arterial tonometry.
Results:
Twenty-four of the 28 included patients could achieve a minimum of 4 measurements. The failure rate was 16% (37 of 238 measurements). The apnea-hypopnea index (AHI) and oxygen desaturation index were consistently lower with radar-based HSAT compared with peripheral arterial tonometry. The variability of the AHI was considerable, with a standard error of measurement of 5.2 events/h (95% confidence interval [CI]: 4.6-5.7 events/h) and a minimal detectable difference of 14.4 events/h (95% CI: 12.7-15.9 events/h). Alcohol consumption partially accounted for the variability, with an AHI increase of 1.7 events/h (95% CI: 0.6-2.8 events/h) for each standard drink. Based on a single measurement, 17% of patients were misdiagnosed and 32% were misclassified for sleep-disordered breathing severity. After 5 measurements, the mean AHI of the measured nights stabilized with no evidence of substantial changes with additional measurements.
Conclusions:
Night-to-night variability is considerable and stable over 10 nights. HSAT using radar-based methods over multiple nights is feasible and well tolerated by patients. It could offer lower costs and allow for multiple-night testing to increase accuracy. However, validation and reducing the failure rate are necessary for implementation in the clinical routine.
Clinical Trial Registration:
Registry: ClinicalTrials.gov; Name: Recording of Multiple Nights Using a New Contactless Device (Sleepiz One Connect) in Obstructive Sleep Apnea; URL: https://clinicaltrials.gov/study/NCT05134402; Identifier: NCT05134402.
Citation:
Tschopp S, Borner U, Caversaccio M, Tschopp K. Long-term night-to-night variability of sleep-disordered breathing using a radar-based home sleep apnea test: a prospective cohort study. J Clin Sleep Med. 2024;20(7):1079-1086.
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