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Psilocybin Exposures Reported to U.S. Poison Centers: National Trends Over a Decade
Rita Farah1, Abigail F Kerns1, Austin C Murray2
1Division of Medical Toxicology, Department of Emergency Medicine, University of Virginia School of Medicine, Charlottesville, Virginia.
Purpose:
We describe trends in psilocybin exposures among adolescents and young adults as reported to US poison centers over the past decade.
Methods:
We queried the National Poison Data System for cases involving psilocybin during January 1, 2013-December 31, 2022. Persons aged 13-25 years were included. We examined exposures to psilocybin by demographics, clinical effects, level of care, and medical outcome.
Results:
During the 10-year study period, 4,055 psilocybin-involved exposures were reported among adolescents and young adults, 2,667 (65.8%) being single substance exposures. Most single substance cases received medical attention (adolescents: 75.3% [n = 1,176], young adults: 72.1% [n = 797]). We did not find significant change in the number of cases during 2013-2018. Cases started increasing in 2019. In 2022, cases more than tripled among adolescents and more than doubled among young adults, compared to 2018 (p < .0001).
Discussion:
Continued national surveillance is critical to determine the impact of psilocybin exposures on youth as it becomes increasingly available.
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