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Related Concept Videos

Dementia01:30

Dementia

113
Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
113
Alzheimer's Disease: Treatment01:22

Alzheimer's Disease: Treatment

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Alzheimer's Disease (AD), a neurodegenerative disorder, is pathologically identified by amyloid plaques and neurofibrillary tangles composed of tau protein. AD pharmacotherapy aims to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms. The treatment is primarily symptomatic and palliative, with no definitive disease-modifying therapy available. Cholinesterase inhibitors, including donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne), are...
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Alzheimer's Disease: Overview01:26

Alzheimer's Disease: Overview

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Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
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Preventive Healthcare Services01:30

Preventive Healthcare Services

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Preventive healthcare services keep people healthy via frequent check-ups, screening, and counseling. They primarily aid in disease prevention rather than treating an acute or chronic illness. Preventive treatment also keeps individuals productive and energetic, allowing them to work well into their retirement years. Examples of preventive care services include:
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Cognitive Development During Adulthood01:30

Cognitive Development During Adulthood

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Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
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Cancer Prevention02:59

Cancer Prevention

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Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
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Related Experiment Video

Updated: Jul 2, 2025

The 4 Mountains Test: A Short Test of Spatial Memory with High Sensitivity for the Diagnosis of Pre-dementia Alzheimer's Disease
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The 4 Mountains Test: A Short Test of Spatial Memory with High Sensitivity for the Diagnosis of Pre-dementia Alzheimer's Disease

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[Prevention of dementia].

Walter M Schippinger1, Gerald Pichler2

  • 1Abteilung für Innere Medizin, Albert-Schweitzer-Klinik, Geriatrische Gesundheitszentren der Stadt Graz, Albert-Schweitzer-Gasse 36, 8020, Graz, Österreich. walter.schippinger@stadt.graz.at.

Der Nervenarzt
|February 28, 2024
PubMed
Summary

Dementia prevalence is rising globally with aging populations. Around 40% of dementia cases are linked to 12 modifiable risk factors, offering opportunities for prevention.

Keywords:
GeriatricsLevel of educationLife expectancyLifestyleRisk factors

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Area of Science:

  • Neurology
  • Public Health
  • Gerontology

Context:

  • Global dementia prevalence is increasing due to rising life expectancy.
  • Dementia poses a significant challenge to future healthcare and social systems.
  • Approximately 40% of new dementia diagnoses are linked to potentially modifiable risk factors.

Purpose:

  • To identify and summarize key risk factors associated with dementia.
  • To inform preventive strategies based on scientific evidence.

Summary:

  • The Lancet commission identified 12 modifiable risk factors for dementia.
  • These include low education, hearing impairment, brain injury, hypertension, diabetes, smoking, alcohol, depression, obesity, social isolation, and air pollution.
  • Evidence is based on longitudinal studies, systematic reviews, and meta-analyses.

Impact:

  • Highlights the potential for dementia prevention through lifestyle and environmental modifications.
  • Provides a framework for public health initiatives targeting dementia risk reduction.
  • Emphasizes the importance of addressing these factors in clinical practice and policy-making.