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Abbreviated Breast MRI: Our Two-Year Initial Experience.
Holly Marshall1, Lauren Burkard-Mandel1, Jerry Hsu1
1University Hospitals Cleveland Medical Center, Department of Radiology, Cleveland, OH, USA.
Journal of Breast Imaging
|February 28, 2024
Summary
Abbreviated breast MRI shows promise as a screening tool, detecting 16 cancers in 1338 women. This method may offer a better cancer detection rate than mammography alone for dense breasts.
Area of Science:
- Radiology
- Oncology
- Medical Imaging
Background:
- Breast cancer screening is crucial for early detection.
- Mammography alone has limitations, especially in women with dense breasts.
- Abbreviated breast MRI (AB-MRI) is an emerging technique for breast cancer screening.
Purpose of the Study:
- To evaluate the two-year experience with abbreviated breast MRI as a primary breast cancer screening tool.
- To assess the cancer detection rate and positive predictive value of AB-MRI.
- To compare AB-MRI's performance with mammography-only screening.
Main Methods:
- Retrospective analysis of 1338 asymptomatic women screened with AB-MRI.
- Studies interpreted by eight breast radiologists using the BI-RADS MRI lexicon.
- AB-MRI protocol completed within 10 minutes, including T1-weighted, fat-saturated, pre- and post-contrast, and short T1 inversion recovery images.
Main Results:
- 16 breast cancers were detected, yielding a cancer detection rate of 12.0 per 1000 women.
- Positive predictive values for BI-RADS 4/5 findings were 14.2% (PPV2) and 18.5% (PPV3).
- All detected cancers were in women with dense or extremely dense breasts; no interval cancers were found within 24 months.
Conclusions:
- Abbreviated breast MRI demonstrates a higher cancer detection rate compared to mammography alone.
- AB-MRI may serve as a valuable supplemental screening method for breast cancer.
- The technique shows potential for identifying cancers in patients with varying risk factors, particularly those with dense breast tissue.
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