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A Spectrum of Metastases to the Breast: Radiologic-Pathologic Correlation.
Jorge L Huayanay Espinoza1, Fiorela N Mego Ramírez2, Henry Guerra Miller2
1Instituto Nacional de Enfermedades Neoplásicas, Department of Radiology, Lima, Peru.
Journal of Breast Imaging
|February 28, 2024
Summary
Metastases to the breast from non-mammary origins are rare but increasingly diagnosed due to advanced imaging. This review clarifies their varied imaging features, stressing radiologic-pathologic correlation for accurate diagnosis in advanced disease.
Area of Science:
- Radiology
- Oncology
- Pathology
Background:
- Intramammary metastases from non-mammary neoplasms are uncommon.
- Melanoma, lymphoma, lung, gynecological carcinomas, and sarcomas are the most frequent origins.
- Increased diagnostic rates are linked to advances in medical imaging technology.
Approach:
- Review of imaging features of intramammary metastases.
- Emphasis on radiologic-pathologic correlation.
- Highlighting the importance of a multidisciplinary approach for diagnosis.
Key Points:
- Imaging characteristics vary based on primary tumor type and dissemination route.
- Metastatic lesions can mimic primary breast cancer or benign breast conditions.
- Specific imaging findings can increase suspicion for metastases within the correct clinical context.
Conclusions:
- Radiologic-pathologic correlation is crucial for diagnosing intramammary metastases.
- A multidisciplinary team approach aids in managing these rare presentations.
- Early recognition is vital, as these metastases often occur in patients with advanced systemic disease.
