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Updated: Jul 2, 2025

A Novel High-Throughput Ex Vivo Ovine Skin Wound Model for Testing Emerging Antibiotics
Published on: September 16, 2022
[Several issues that need attention to improve the diagnosis and treatment level of infectious wounds]
1Department of Burns and Plastic Surgery & Wound Repair Surgery, Lanzhou University Second Hospital, Lanzhou 730030, China.
Abstract:
Wound infection is an inflammatory response of the host to pathogenic microorganisms. It is a complex pathological process that may manifest either as a rapid onset acute wound infection, or as a prolonged chronic wound infection. Infectious wounds refer to acute or chronic wounds where infection has occurred, and their diagnosis and treatment involve many links, any loopholes in any aspect can lead to treatment failure. How to improve the diagnosis and treatment level of infectious wounds? This article proposed and discussed several issues, such as biofilm and drug resistance of bacteria, new materials and new-type dressings, special types of infectious wounds, and the combined application of various treatment techniques that need attention, and intended to attract the attention of peers. At the same time, it advocated for full attention to research results in the relevant fields and continuously emerging new technologies, concepts, materials, and methods, and applying them to the diagnosis and treatment of infectious wounds to benefit the majority of patients.
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