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Updated: Jul 2, 2025

A Novel Approach to Monitoring Graft Neovascularization in the Human Gingiva
Published on: January 12, 2019
Single-flap approach versus without concentrate growth factor in the treatment of periodontal supra-osseous defects:
Naglaa El-Wakeel1, Lobna Mohamed Abd-Elaziz1
1Oral Medicine and Periodontology Department, Faculty of Dentistry, Al-Azhar University (Girls Branch), Cairo, Egypt.
Objectives:
We aimed to compare treatment outcomes of periodontal supra-bony defects using single flap (SFA) plus concentrate growth factor versus SFA alone.
Methods:
32 supra-bony periodontal defects were randomly assigned to test and control groups. Outcome variables were clinical attachment level (primary outcome). Probing pocket depths, gingival recessions, bone gain, post-surgical pain using visual analogue scale and wound healing index were recorded as secondary outcomes. Clinical and radiographic assessments were recorded at baseline and 6 months after treatment, whereas pain score and wound healing index were recorded within 10 days after surgery.
Results:
Test group showed a significant improvement in all tested parameters compared to control group (P-value ≤ 0.05). Better patient centered outcomes (wound healing and pain scores) were highly achieved in the test group compared to controls.
Conclusion:
The tested combined approach offers better periodontal and patient centered treatment outcomes in management of periodontal supra-bony defects.
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