Metachronous seminoma of the pineal region and right testis. Case report

The case history of a 23-year-old patient suffering from germinoma of the pineal region, who later developed a seminoma of the right testis, is reported. The possibility that the testicular tumor was a metastasis from the pineal neoplasia appears unlikely. The question of whether the pineal germinoma represented a metastasis from an occult testicular seminoma or an autochthonous tumor is discussed. The latter hypothesis is considered the most likely. The present report appears to support the multiple primary origin of, at least some, germ cell tumors.