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Updated: Jul 22, 2026

Programmed Electrical Stimulation in Mice
Published on: May 26, 2010
[Development and clinical value of programmed ventricular stimulation in coronary artery disease and dilated
1, Karlsruhe, Deutschland. prof.gonska@vincentius-ka.de.
Abstract:
Programmed ventricular stimulation (PVS), a clinical tool introduced in the early 1980s, aims to prove the electrical vulnerability of the heart and, independent of spontaneous arrhythmia variability, to trigger arrhythmias under controlled conditions. A specific response is the inducibility of monomorphic sustained ventricular tachycardia. This depends on the underlying heart disease, e.g., only for coronary artery disease but not for nonischemic diseases. The value of pharmacologic arrhythmia control as serial electrical testing is uncertain. Up to now there seems to be no prognostic value of PVS concerning sudden cardiac death. PVS is used as a tool to monitor the results of ventricular tachycardia (VT)-catheter ablation in patients who were primarily inducible.
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