Retinal arterial and vein occlusion: is surgery ever indicated?

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A Murine Model of Ischemic Retinal Injury Induced by Transient Bilateral Common Carotid Artery Occlusion
05:20

A Murine Model of Ischemic Retinal Injury Induced by Transient Bilateral Common Carotid Artery Occlusion

Published on: November 12, 2020

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Kazuaki Kadonosono1, Maiko Inoue, Yasuo Yanagi

  • 1Department of Ophthalmology and Micro-technology, Yokohama City University, School of Medicine, Yokohama, Japan.

Current Opinion in Ophthalmology
|February 29, 2024
PubMed

Insights

Surgical innovations offer new hope for retinal vascular occlusions. Micro-cystotomy and robotic-assisted cannulation show promise for treating central retinal vein occlusion (CRVO) and central retinal artery occlusion (CRAO).

Area of Science:

  • Ophthalmology
  • Retinal Vascular Diseases
  • Surgical Innovation

Background:

  • Central retinal vein occlusion (CRVO) and central retinal artery occlusion (CRAO) present significant challenges in treatment.
  • Current therapies, like anti-VEGF for CRVO, have limitations, and CRAO lacks established treatments.
  • Refractory macular edema in CRVO and occlusive events in CRAO represent unmet clinical needs.

Approach:

  • Review of recent surgical advancements for CRVO and CRAO.
  • Exploration of micro-cystotomy for refractory macular edema secondary to ischemic CRVO.
  • Evaluation of robotic-assisted cannulation techniques for CRAO, including thrombus removal with tissue plasminogen activator (tPA).

Key Points:

  • Micro-cystotomy demonstrates a 78% success rate in treating refractory macular edema in CRVO.
  • Robotic assistance enhances the precision and ease of cannulation procedures for CRAO.
  • Tissue plasminogen activator (tPA) shows efficacy in CRAO cases involving thrombus.

Conclusions:

  • Surgical interventions like micro-cystotomy and robotic-assisted cannulation are advancing treatment options for CRVO and CRAO.
  • These innovative surgical techniques address limitations of current medical therapies.
  • Future developments in surgical technology promise improved management of retinal vascular occlusive diseases.
Abstract

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