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Area of Science:

  • Hepatology
  • Addiction Medicine
  • Public Health

Background:

  • Individuals with chronic hepatitis C virus (HCV) exhibit higher smoking prevalence.
  • Smoking exacerbates HCV-related complications, such as hepatocellular carcinoma.
  • Factors influencing cigarette use among people with HCV (PWHC) are not well understood.

Purpose of the Study:

  • To explore beliefs and behaviors associated with cigarette use among PWHC.
  • To identify reasons for smoking and barriers to quitting among PWHC.
  • To understand the relationship between HCV and smoking behaviors.

Main Methods:

  • Qualitative data collected from two focus groups (n=15) of PWHC who currently smoke.
  • Semi-structured interview guide used to explore smoking reasons, quitting barriers, and HCV-smoking links.
  • Verbatim transcripts analyzed using thematic coding by four researchers.

Main Results:

  • Primary reasons for smoking included addiction, stress management, drug substitution, and social norms.
  • Motivations for quitting centered on health and achieving freedom from all substance use.
  • Barriers to quitting encompassed stress coping, weight gain concerns, and insufficient support/education.

Conclusions:

  • PWHC identified both HCV-related and unrelated factors influencing smoking and cessation.
  • Cessation interventions should consider HCV-specific triggers, like stress from diagnosis or cure.
  • Further research is needed to develop effective cessation treatments tailored for PWHC.