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Updated: Aug 6, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
A guidewire-free approach for percutaneous closure of left ventricular pseudoaneurysm
Tahir Bezgin1, Aziz Inan Celik1, Nart Zafer Baytugan1
1Department of Cardiology, Gebze Fatih State Hospital, Heart Center, Kocaeli, Turkey.
Insights
A 78-year-old male with heart failure experienced severe shortness of breath (dyspnea) despite optimal medical therapy. This case highlights challenges in managing advanced heart failure symptoms in patients with multiple comorbidities.
Area of Science:
- Cardiology
- Internal Medicine
- Geriatrics
Background:
- The patient is a 78-year-old male with a significant medical history including coronary artery disease (CAD) status post-coronary artery bypass grafting (CABG), heart failure with mildly reduced ejection fraction (HFmrEF), diabetes mellitus (DM), and transient ischemic attack (TIA).
- He was receiving optimal medical therapy for his conditions.
Observation:
- The patient presented to the emergency department with acute-onset dyspnea.
- His symptoms were classified as New York Heart Association (NYHA) Class 4, indicating severe limitations in physical activity.
Findings:
- Despite adherence to optimal medical therapy, the patient experienced a significant worsening of heart failure symptoms, manifesting as severe dyspnea.
- The presence of multiple comorbidities (CAD, HFmrEF, DM, TIA) likely contributed to the complexity of his condition and refractoriness to standard treatment.
Implications:
- This case underscores the challenges in managing advanced heart failure in elderly patients with multiple comorbidities.
- It suggests a potential need for exploring advanced or alternative therapeutic strategies when optimal medical therapy proves insufficient for symptom control.
- Further investigation into the specific mechanisms driving refractory dyspnea in this patient population may be warranted.
Abstract:
A 78-year-old male patient with a history of coronary artery disease (he had undergone coronary artery bypass surgery 4 years ago), heart failure with mildly reduced ejection fraction, diabetes mellitus, and transient ischemic attack presented to the emergency department with complaints of dyspnea (New York Heart Association Class 4) despite the optimal medical therapy.

