Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

89
The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
89
Peptic Ulcer Disease I: Introduction01:30

Peptic Ulcer Disease I: Introduction

168
Peptic Ulcer Disease (PUD) is characterized by mucosal excavation in the esophagus, stomach, pylorus, or duodenum. It can manifest as acute or chronic based on the extent and duration of mucosal involvement.
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
168
Acute Pancreatitis I: Introduction01:27

Acute Pancreatitis I: Introduction

360
Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
360
Acute Pancreatitis II: Clinical Manifestations and Management01:30

Acute Pancreatitis II: Clinical Manifestations and Management

124
Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
124
Pathophysiology of Peptic Ulcer Disease: Mucosal Defense Factors01:24

Pathophysiology of Peptic Ulcer Disease: Mucosal Defense Factors

429
Peptic ulcer disease, commonly called PUD, represents a multifaceted condition characterized by disruptions in the lining of the gastrointestinal (GI)  tract. Central to the protection of the gastrointestinal lining is the mucosal-bicarbonate barrier. This physiological defense mechanism is a formidable shield against the corrosive effects of gastric acid and pepsin secretion in the stomach. Its role is pivotal in maintaining the structural integrity of the stomach's inner lining.
429
Pathophysiology of Peptic Ulcer Disease: Injurious Factors01:22

Pathophysiology of Peptic Ulcer Disease: Injurious Factors

591
Peptic ulcers are sores on the stomach's inner lining and the upper small intestine, which are the result of disruptions in the mucosal layer that houses parietal cells which produce gastric acid, and chief cells which secrete pepsinogen.
In the antrum region, G cells secrete the gastrin hormone that binds to gastrin-cholecystokinin-B (CCK2) receptors on parietal and enterochromaffin-like (ECL) cells in the fundic glands. Simultaneously, the vagus nerve releases acetylcholine, which binds...
591

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Differential survival with adjuvant immunotherapy in stage III acral versus non-acral melanoma.

Journal of the European Academy of Dermatology and Venereology : JEADV·2026
Same author

Radiation Therapy Utilization and Survival Associations in Metastatic Merkel Cell.

International journal of dermatology·2026
Same author

Therapeutic Infliximab Levels Are Associated With Improved Clinical Outcomes in Hidradenitis Suppurativa: A Pilot Retrospective Cohort Study.

Journal of the American Academy of Dermatology·2026
Same author

Delayed Surgical Treatment Is Associated with Positive Margins and Worse Long-Term Survival in Early-Stage Vulvar Melanoma: A Retrospective National Cancer Database Study.

Journal of the American Academy of Dermatology·2026
Same author

Impact of immune checkpoint inhibitors on enfortumab vedotin cutaneous toxicity: A systematic clinicopathologic review.

Journal of the American Academy of Dermatology·2026
Same author

Criteria for Hidradenitis Suppurativa Competence Centers.

Dermatology and therapy·2026

Related Experiment Video

Updated: Jul 1, 2025

Morphological and Compositional Analysis of Neutrophil Extracellular Traps Induced by Microbial and Chemical Stimuli
14:05

Morphological and Compositional Analysis of Neutrophil Extracellular Traps Induced by Microbial and Chemical Stimuli

Published on: November 4, 2022

2.5K

Neutrophilic Panniculitides.

Ganesh B Maniam1, Anne Coakley1, Giang Huong Nguyen1

  • 1Mayo Clinic Department of Dermatology, 200 First Street Southwest, Rochester, MN 55905, USA.

Dermatologic Clinics
|February 29, 2024
PubMed
Summary

Neutrophilic panniculitides are diverse inflammatory skin conditions. Diagnosis and treatment are challenging due to varied presentations and limited standardized therapies, highlighting the need for collaborative research.

Keywords:
Alpha-1 antitrypsin deficiencyDrug-induced panniculitisNeutrophilic dermatosesNeutrophilic panniculitisPancreatic panniculitisPfeifer-Weber-Christian diseaseSweet syndromesubcutaneous sweet syndrome

More Related Videos

Author Spotlight: Neutrophil Extracellular Traps Imaging in Human and Mouse Tissues
07:36

Author Spotlight: Neutrophil Extracellular Traps Imaging in Human and Mouse Tissues

Published on: August 18, 2023

6.4K
Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
07:15

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils

Published on: January 21, 2020

11.4K

Related Experiment Videos

Last Updated: Jul 1, 2025

Morphological and Compositional Analysis of Neutrophil Extracellular Traps Induced by Microbial and Chemical Stimuli
14:05

Morphological and Compositional Analysis of Neutrophil Extracellular Traps Induced by Microbial and Chemical Stimuli

Published on: November 4, 2022

2.5K
Author Spotlight: Neutrophil Extracellular Traps Imaging in Human and Mouse Tissues
07:36

Author Spotlight: Neutrophil Extracellular Traps Imaging in Human and Mouse Tissues

Published on: August 18, 2023

6.4K
Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
07:15

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils

Published on: January 21, 2020

11.4K

Area of Science:

  • Dermatology
  • Immunology
  • Pathology

Background:

  • Neutrophilic panniculitides represent a complex group of inflammatory diseases.
  • These conditions present diagnostic challenges due to variable clinical manifestations and systemic involvement.

Purpose of the Study:

  • To review the epidemiology, pathogenesis, clinicopathological features, diagnosis, and treatment of selected neutrophilic panniculitides.
  • To highlight the diagnostic challenges and current therapeutic limitations.

Main Methods:

  • Literature review of selected neutrophilic panniculitis entities.
  • Synthesis of information on clinical presentation, diagnostic criteria, and treatment approaches.

Main Results:

  • Neutrophilic panniculitides exhibit heterogeneous presentations, complicating diagnosis.
  • Current treatment strategies lack standardization, with many anecdotal reports and limited evidence.
  • Systemic involvement is common, necessitating comprehensive patient evaluation.

Conclusions:

  • There is a significant unmet need for standardized diagnostic and therapeutic guidelines.
  • Multi-institutional collaboration is crucial for advancing research and improving patient care for rare neutrophilic panniculitides.