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Related Concept Videos

Appendicitis-I: Introduction01:22

Appendicitis-I: Introduction

140
The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
140
Appendicitis-II: Diagnostic Studies and Management01:29

Appendicitis-II: Diagnostic Studies and Management

80
Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
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Acute Pancreatitis II: Clinical Manifestations and Management01:30

Acute Pancreatitis II: Clinical Manifestations and Management

124
Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
124
Acute Pharyngitis01:30

Acute Pharyngitis

660
Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
660
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

244
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
244
Tonsillitis I: Introduction01:30

Tonsillitis I: Introduction

248
Tonsillitis is inflammation of the tonsils, which are two lymphoid tissue masses at the back of the throat. This condition can cause discomfort and irritation in the throat.
Etiology
Three primary contributing factors have been identified.
248

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Related Experiment Video

Updated: Jul 1, 2025

Chronic Salmonella Infection Induced Intestinal Fibrosis
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Can Salmonella typhi Cause Acute Appendicitis?

Reda H Mithany1, Amarah Shaikh2, Catherine Scott2

  • 1Laparoscopic Colorectal Surgery, Kingston Hospital NHS Foundation Trust, Kingston Upon Thames, GBR.

Cureus
|March 1, 2024
PubMed
Summary
This summary is machine-generated.

Salmonella typhi, a bacterium causing typhoid fever, can rarely lead to appendicitis. This case report details a patient diagnosed with S. typhi-induced appendicitis, emphasizing timely diagnosis and treatment.

Keywords:
acute appendicitisappendicectomycase reportcauses of acute appendicitissalmonella typhiterminal ileitistyphlitis

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Area of Science:

  • Gastroenterology
  • Infectious Diseases
  • Surgical Pathology

Background:

  • Salmonella typhi is a bacterium primarily known for causing typhoid fever and systemic infections.
  • Localized gastrointestinal complications, such as appendicitis, are rare but recognized manifestations of S. typhi infection.
  • Understanding the varied clinical presentations of S. typhi is crucial for effective patient management.

Observation:

  • A 55-year-old patient presented with symptoms indicative of gastrointestinal distress.
  • Clinical evaluation, laboratory tests, and radiological imaging confirmed appendicitis.
  • Diagnostic investigations revealed Salmonella typhi as the causative agent of the appendicitis.

Findings:

  • The case report documents a rare instance of Salmonella typhi-induced appendicitis.
  • Detailed patient history, clinical presentation, and diagnostic findings are presented.
  • Successful management and positive patient outcomes were achieved through prompt intervention.

Implications:

  • This case underscores the importance of considering S. typhi in the differential diagnosis of appendicitis, especially in endemic regions.
  • Highlights the need for thorough etiological investigation in appendicitis cases to identify infectious causes.
  • Emphasizes the significance of prompt diagnosis and appropriate antimicrobial therapy for Salmonella-induced appendicitis to prevent complications and ensure favorable outcomes.