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Exercise-based gaming in patients with multiple sclerosis: A systematic review and meta-analysis
Amal Mohamed Elhusein1, Hammad Ali Fadlalmola2, Eltayeb Mohammed Awadalkareem3
1Nursing Department, College of Applied Medical Sciences, University of Bisha, Bisha, Saudi Arabia.
Belitung Nursing Journal
|March 1, 2024
Summary
Exergaming shows potential benefits for multiple sclerosis (MS) patients, improving some motor and cognitive functions. While not superior to conventional therapy for all outcomes, it offers a flexible, home-based rehabilitation option.
Area of Science:
- Neuroscience
- Rehabilitation Medicine
- Digital Health
Background:
- Multiple sclerosis (MS) significantly impacts patients' daily lives, particularly balance.
- Exergaming offers an engaging, multisensory approach to rehabilitation for MS patients.
Purpose of the Study:
- To systematically review and meta-analyze the evidence on exergaming for multiple sclerosis treatment.
- To evaluate exergaming's impact on cognitive, motor, and psychological outcomes in MS patients.
Main Methods:
- Systematic review and meta-analysis of 27 studies.
- Searched five databases up to June 2023.
- Assessed risk of bias using ROB1 and NIH tools.
Main Results:
- Exergaming showed significant improvements in the Symbol Digit Modalities Test (SDMT) compared to no intervention.
- Exergaming improved the 6-minute walking test and Berg Balance Scale compared to no intervention.
- Exergaming favored the Modified Fatigue Impact Scale (MFIS) in the Conventional Physiotherapy and Rehabilitation interventions (CPRh) subgroup.
Conclusions:
- Exergaming demonstrates potential for improving cognitive, motor, and psychological outcomes in MS patients.
- Home-based exergaming can be a valuable alternative or supplement to traditional rehabilitation.
- Further research is needed to determine optimal exergaming protocols and long-term benefits.

