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Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus
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Ultrasound findings in early congenital syphilis: Two case reports and literature review

Giulia Muzi1, Dolores Ferrara2, Rosanna Mamone2

  • 1Chair of Pediatrics, NESMOS Department, Faculty of Medicine and Psychology, Sapienza University of Rome, Sant'Andrea University Hospital, Rome, Italy.

Radiology Case Reports
|March 1, 2024
PubMed

Insights

Congenital syphilis (CS) in infants can cause severe symptoms like liver failure. This study highlights key ultrasound findings in early congenital syphilis, aiding diagnosis and treatment.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Radiology

Background:

  • Congenital syphilis (CS) arises from untreated maternal syphilis during pregnancy.
  • Early CS manifests before two years of age with potential for severe systemic involvement.
  • Current data on specific ultrasound (US) findings in early CS, particularly intestinal and brain, are limited.

Observation:

  • Two cases of early congenital syphilis are presented with severe clinical presentations.
  • Key symptoms included liver failure, edema, organomegaly, and respiratory distress.
  • Radiological assessment focused on liver, intestinal, and brain ultrasound findings.

Findings:

  • The study details unique liver, intestinal, and brain ultrasound characteristics in early CS.
  • Abdominal US data for early CS is scarce, with no prior scientific data on intestinal and brain US findings.
  • Peculiar radiological findings were observed and documented.

Implications:

  • Enhanced understanding of US findings can improve early diagnosis of congenital syphilis.
  • Improved diagnostic capabilities may lead to better therapeutic strategies for affected infants.
  • This research addresses a critical knowledge gap in pediatric infectious disease imaging.

Keywords:
Brain ultrasoundCongenital syphilisIntestinal ultrasoundNeonatal ultrasoundSyphilisUltrasound

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