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LSG vs OAGB: 7-Year Follow-up Data of a Randomised Control Trial and Comparative Outcome Based on BAROS Score
Mayank Jain1, Om Tantia2, Ghanshyam Goyal3
1Department of Minimal Access & Bariatric Surgery, Synergyplus Hospital, NH2, Near Guru Ka Taal, Agra, 282007, Uttar Pradesh, India.
Obesity Surgery
|March 1, 2024
Summary
One anastomosis gastric bypass (OAGB) shows superior long-term weight loss and outcomes compared to laparoscopic sleeve gastrectomy (LSG). OAGB resulted in higher percent excess weight loss and percent total weight loss at 7 years.
Area of Science:
- Bariatric Surgery
- Metabolic Surgery
- Obesity Management
Background:
- Morbid obesity presents significant health challenges requiring effective long-term management strategies.
- Laparoscopic sleeve gastrectomy (LSG) and one anastomosis gastric bypass (OAGB) are established bariatric procedures.
- Comparative long-term data on LSG versus OAGB outcomes are crucial for clinical decision-making.
Purpose of the Study:
- To compare the long-term efficacy of LSG and OAGB in patients with morbid obesity.
- To evaluate outcomes using the Bariatric Analysis Reporting and Outcome System (BAROS) score at 7 years post-surgery.
- To assess changes in body weight, quality of life, and comorbidity resolution.
Main Methods:
- A randomized controlled trial involving 201 patients (100 LSG, 101 OAGB) operated between 2013-2015.
- Analysis of total body weight (TBW), body mass index (BMI), percent excess weight loss (%EWL), and percent total weight loss (%TWL) at 7-year follow-up.
- Assessment of quality of life (QoL) scores, comorbidity resolution, and BAROS outcomes.
Main Results:
- At 7 years, both LSG and OAGB demonstrated significant reductions in TBW and BMI.
- OAGB achieved higher mean %EWL (59.99% vs. 50.78%) and %TWL (27.71% vs. 23.22%) compared to LSG.
- Significantly more OAGB patients (68.76%) achieved very good or excellent BAROS outcomes versus LSG patients (36.37%).
Conclusions:
- Both LSG and OAGB are effective long-term bariatric procedures for morbid obesity.
- OAGB demonstrates superior long-term weight loss and patient outcomes compared to LSG.
- The BAROS score highlights the significant advantage of OAGB in achieving excellent long-term results.

