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Self-Reported Everyday Functioning After COVID-19 Infection.
Theodore J Iwashyna1,2,3,4, Valerie A Smith5,6,7, Sarah Seelye1
1VA Center for Clinical Management Research, Ann Arbor VA, Ann Arbor, Michigan.
JAMA Network Open
|March 1, 2024
Summary
Many veterans experienced reduced everyday functioning during the pandemic, irrespective of COVID-19 infection status. Further research with larger samples is required to confirm these findings on long COVID effects.
Area of Science:
- Public Health
- Infectious Diseases
- Longitudinal Studies
Background:
- Assessing the long-term impact of COVID-19 on daily life is crucial.
- Understanding functional changes post-infection informs recovery and support strategies.
Purpose of the Study:
- To investigate the impact of COVID-19 on everyday functioning in veterans 18 months post-infection.
- To compare functional outcomes between veterans with and without a history of COVID-19.
Main Methods:
- A cohort study involving 186 veterans with COVID-19 and 186 matched controls from the US Veterans Affairs.
- Target trial emulation principles were used for matching based on 39 pre-infection variables.
- Weighted logistic and linear regressions analyzed differences in self-reported everyday functioning.
Main Results:
- A higher proportion of COVID-19 survivors (44.9%) reported reduced functioning compared to controls (35.3%) 18 months post-infection.
- No significant association was found between COVID-19 infection and fatigue, pain, daily living limitations, mobility, employment, or quality of life.
Conclusions:
- Many veterans reported significant declines in everyday functioning during the pandemic, regardless of COVID-19 infection.
- The study highlights the widespread impact of the pandemic on functioning, necessitating further investigation with larger cohorts.
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