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Murine Oropharyngeal Aspiration Model of Ventilator-associated and Hospital-acquired Bacterial Pneumonia
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Bacterial profiles detected in ventilator-associated pneumonia in Japan: A systematic review

Hiroshi Moro1, Nobumasa Aoki1, Hiroyuki Matsumoto2

  • 1Department of Respiratory Medicine and Infectious Diseases, Niigata University Graduate School of Medical and Dental Science, 1-757 Asahimachi-dori, Chuo-ku, Niigata City, Niigata, 952-8510, Japan.

Respiratory Investigation
|March 1, 2024
PubMed

Insights

This study identified the main bacteria causing ventilator-associated pneumonia (VAP) in Japan. Pseudomonas aeruginosa and MRSA were most common, with a high rate of multidrug-resistant (MDR) pathogens found.

Area of Science:

  • Infectious Diseases
  • Microbiology
  • Critical Care Medicine

Background:

  • Ventilator-associated pneumonia (VAP) is a significant hospital-acquired infection.
  • Identifying causative pathogens is crucial for effective treatment and infection control.

Conclusions:

  • P. aeruginosa and MRSA are the leading causes of VAP in Japan.
  • A high prevalence of MDR pathogens necessitates careful consideration in empirical treatment strategies.
  • Understanding regional pathogen distribution is vital for optimizing VAP management.
Keywords:
Methicillin-resistant Staphylococcus aureusPseudomonas aeruginosaSystematic reviewVentilator-associated pneumonia

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