[Exposure to acetone: experimental study of absorption and pulmonary elimination in normal subjects]

Alveolar (CA) and mixed expired air (CE) acetone concentrations were measured in 15 healthy volunteer subjects, exposed to acetone (CI) in an exposure chamber (exposure range: 48-565 mg/m3) both at rest and during exercise (50 W). The Relative Uptake (R = 1-CE/CI) was 0.54 at rest (120' and 240') and 0.55 during exercise (120', 50 W). Ca:CI ratio was 0.24 at rest. CE:CI and CA:CI ratio was constant throughout the exposure time, both at rest and during exercise.