Promoting bond durability by a novel fabricated bioactive dentin adhesive

Area of Science:

• Biomaterials Science
• Dental Materials Science
• Nanotechnology in Dentistry

Background:

• Dentin adhesives are crucial for durable dental restorations.
• Improving the long-term stability and sealing ability of dentin bonding remains a challenge.
• Bioactive materials offer potential for enhanced mineralization and reduced secondary caries.

Purpose of the Study:

• To develop a bioactive dentin adhesive incorporating phosphorus-silicate-calcium (PSC) glass particles.
• To evaluate the effect of this bioactive adhesive on promoting dentin bonding durability.
• To assess the mineralization capability and long-term performance of the new adhesive.

Main Methods:

• Prepared bioactive glass (PSC) and characterized its mineralization potential using SEM and TEM.
• Formulated a bioactive dentin adhesive (PSC-Bond) with 20 wt% PSC particles.
• Evaluated degree of conversion, microtensile bond strength (μTBS), and film thickness.
• Assessed long-term bonding durability and microleakage after aging in simulated body fluid for up to 6 months.

Main Results:

• PSC demonstrated effective mineralization and induced type I collagen mineralization.
• PSC-Bond exhibited a degree of conversion of 62.65%, μTBS of 39.25 MPa, and film thickness of 17.00 μm.
• PSC-Bond formed hydroxyapatite and showed good interface mineralization.
• After 6 months, PSC-Bond significantly outperformed the control in μTBS and reduced microleakage.

Conclusions:

• The developed bioactive dentin adhesive (PSC-Bond) demonstrates enhanced mineralization capabilities.
• PSC-Bond maintains stable bond strength and reduces interfacial microleakage over time.
• This bioactive approach shows promise for improving the longevity of dental adhesive restorations and potentially preventing secondary caries.