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Related Concept Videos

Decreased Body Temperature01:29

Decreased Body Temperature

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A decreased body temperature can occur in patients with hypothermia and frostbite. Heat loss with extended cold exposure overpowers the body's ability to create heat, resulting in hypothermia. Core temperature readings help classify hypothermia. Mild hypothermia is temperatures between 32 °C (89.6 °F) and 35°C (95 °F) and is caused by impaired thermoregulation. Moderate hypothermia is temperatures between 28 C (82.4 °F) and 32 °C (89.6 °F) caused by...
615
Methods of reducing fever01:22

Methods of reducing fever

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The signs and symptoms of fever include hot and dry skin, flushed face, thirst, muscle aches, anorexia, headache, tachycardia, tachypnea, and fatigue. Elevated body temperature is reduced using two methods: pharmacological and nonpharmacological. Proper identification and treatment of the root cause of a fever is of utmost importance.
Pharmacological Methods of Reducing Fever:
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Inflammatory Response I: Vascular and Cellular01:30

Inflammatory Response I: Vascular and Cellular

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The inflammatory response is the body's defense against infection, injury, or irritation from bacteria, trauma, toxins, or heat. Inflammation helps locate and destroy pathogens and remove damaged tissue elements to heal the body. During this initial phase, fluid, blood products, and nutrients migrate to the injured area, resulting in redness, heat, swelling, ache, and loss of function. Moreover, signs of systemic inflammation include fever, increased WBC count, malaise, anorexia, nausea,...
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Increased Body Temperature01:25

Increased Body Temperature

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A body temperature above  38°C  (100.4 °F) is known as fever or pyrexia, and a person with fever is termed 'febrile.' Typically, the hypothalamus, a part of the brain that acts as the body's thermostat, regulates body temperature through a thermoregulatory setpoint. It receives signals from cold and warm thermal receptors throughout the body and adjusts the body's temperature accordingly. Fever occurs when this hypothalamic setpoint is altered, usually in...
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Factors Affecting Body Temperature01:28

Factors Affecting Body Temperature

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As a nurse, it is vital to understand the factors affecting body temperature to monitor variations and effectively evaluate deviations from regular.
Factors may  include:
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Burn Injuries01:22

Burn Injuries

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Burn injuries occur when the skin and underlying tissues are damaged due to exposure to heat, electricity, chemicals, radiation, or friction. They can vary in severity, from minor superficial burns to severe deep burns that can be life-threatening.
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
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Updated: Jul 1, 2025

Strategies for Study of Neuroprotection from Cold-preconditioning
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Update on Cold-Induced Injuries.

Francesco M Egro1, Eva Roy2, Jonathan Friedstat3

  • 1Department of Plastic Surgery, University of Pittsburgh Medical Center, 1350 Locust Street, Suite G103, Pittsburgh, PA 15219, USA; Department of Surgery, University of Pittsburgh Medical Center, 1400 Locust Street, Pittsburgh, PA 15219, USA.

Clinics in Plastic Surgery
|March 1, 2024
PubMed
Summary
This summary is machine-generated.

Cold-induced injuries pose significant risks, including amputation and death. Prompt diagnosis and treatments like thrombolytics are crucial for improving tissue perfusion and patient outcomes.

Keywords:
Cold injuriesCold-induced injuriesFrostbiteFrostnipOutcomesThrombolytics

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Area of Science:

  • Medical research
  • Trauma surgery
  • Emergency medicine

Background:

  • Cold-induced injuries present severe challenges for burn surgeons.
  • These injuries can lead to devastating patient outcomes such as amputations, long-term disability, and mortality.
  • Timely assessment and diagnosis are critical for effective management.

Purpose of the Study:

  • To provide an updated review of evidence-based assessment and management strategies for cold-induced injuries.
  • To examine current therapeutic options and their impact on patient outcomes.
  • To discuss future directions in the treatment of cold-induced injuries.

Main Methods:

  • Literature review of current evidence on cold-induced injuries.
  • Analysis of various therapeutic interventions, including topical, oral, intravenous agents, and thrombolytics.
  • Evaluation of patient outcomes and emerging treatment modalities.

Main Results:

  • Various therapeutic agents have been investigated to mitigate the effects of cold injuries.
  • Thrombolytic therapy demonstrates significant promise in enhancing tissue perfusion.
  • Evidence-based assessment and management protocols are essential for optimizing patient recovery.

Conclusions:

  • Cold-induced injuries require rapid and accurate diagnosis for optimal patient care.
  • Thrombolytics represent a promising therapeutic avenue for improving tissue perfusion in cold injuries.
  • Continued research is needed to further refine management strategies and improve outcomes for patients with cold-induced injuries.