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[Short-term outcome of infants hospitalized for an attack of acute bronchiolitis]
Insights
Recurrent wheezing in infants with acute bronchiolitis can be predicted by IgE levels, family history of atopy, and lung imaging. Early identification aids in managing chronic respiratory symptoms.
Area of Science:
- Pediatrics
- Pulmonology
- Immunology
Context:
- Acute bronchiolitis is a common respiratory infection in infants.
- Understanding long-term outcomes is crucial for clinical management.
Purpose:
- To identify predictors of recurrent wheezing and chronic bronchopulmonary symptoms following acute bronchiolitis.
- To analyze the clinical, biological, and radiological findings in hospitalized infants.
Summary:
- A prospective study followed 74 infants with acute bronchiolitis for 18 months.
- Recurrent wheezing was associated with elevated IgE levels, family history of atopy, and radiological pulmonary hyperexpansion.
- No significant difference in disease progression was observed between infants with and without initial wheezing.
Impact:
- Identifies key factors for predicting long-term respiratory issues in infants post-bronchiolitis.
- Informs clinical practice for risk stratification and targeted interventions.
- Highlights the importance of a multidisciplinary approach including allergy and radiology.
Abstract:
The authors report the clinical, biological, radiological findings of 109 infants hospitalised for acute bronchiolitis. A prospective study was possible in 74 of them with an average of follow up of 18 months. After the admission, 31% were asymptomatic, 56% suffered at least one or several episode of wheezing, 13% have recurrent or chronic bronchopulmonary symptoms including cough and airway obstruction. Three points appeared determinant to predict recurrent wheezing: the rate of IgE, a familial history of atopy, and radiological pulmonary hyperexpansion. There was no statistic difference of evolution between the infants with wheezing at the admission and the others. The main prospective studies were analysed for discussion of the prognostic problems.