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Updated: Jul 1, 2025

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
Published on: January 11, 2020
The SAFE procedure: a practical stopping heuristic for active learning-based screening in systematic reviews and
Josien Boetje1, Rens van de Schoot2
1Research Group Digital Ethics, Knowledge Center Learning and Innovation (LENI), Archimedes Institute, HU University of Applied Sciences Utrecht, Utrecht, the Netherlands. josien.boetje@hu.nl.
Determining when to stop active learning in systematic reviews is challenging. The new SAFE procedure provides conservative stopping heuristics to minimize missing relevant papers while balancing screening costs.
Area of Science:
- Information Science
- Medical Informatics
- Bibliometrics
Background:
- Active learning is increasingly used for screening large datasets in systematic reviews and meta-analyses.
- The goal of active learning is to identify relevant records efficiently by improving predictions on unlabeled data.
- A key challenge is determining the optimal stopping point to balance labeling costs and the risk of excluding relevant records.
Purpose of the Study:
- To introduce the SAFE procedure, a set of practical stopping heuristics for active learning in systematic review screening.
- To provide clear guidelines for deciding when to end the active learning process in screening software.
- To minimize the risk of missing relevant papers during the screening process.
Main Methods:
- The study proposes the SAFE (Stopping Appropriately for Efficiency) procedure.
- This procedure utilizes a mix of stopping heuristics to guide the termination of active learning.
- It aims to balance the cost of continued screening with the risk of erroneous exclusions.
Main Results:
- The SAFE procedure offers a practical and conservative approach to ending active learning.
- It helps reviewers make informed decisions by balancing screening costs against the risk of missing relevant records.
- The heuristics are designed to minimize the chance of excluding valuable papers.
Conclusions:
- The SAFE procedure provides a valuable tool for optimizing active learning in systematic reviews.
- It addresses the critical challenge of determining when to stop the screening process effectively.
- The decision to stop active learning requires careful consideration of dataset specifics and potential model errors.
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