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COVID-19 associated anosmia in pediatric patients: subject publications review

Olena V Lobova1, Iryna V Avramenko2, Iryna I Shpak1

  • 1KYIV MEDICAL UNIVERSITY, KYIV, UKRAINE.

Wiadomosci Lekarskie (Warsaw, Poland : 1960)
|March 3, 2024
PubMed

Insights

COVID-19 associated anosmia in children is rare but can be the sole indicator of infection. Early detection and diagnosis are vital for pediatric patients, as this symptom may be the only sign of illness.

Area of Science:

  • Otolaryngology
  • Infectious Diseases
  • Pediatrics

Background:

  • Pediatric COVID-19 cases are less common and typically milder than in adults.
  • Anosmia (loss of smell) can be a unique or primary symptom in children infected with SARS-CoV-2.
  • Recognizing anosmia is critical for timely diagnosis and management in pediatric populations.

Purpose of the Study:

  • To comprehensively review current literature on COVID-19-associated anosmia in pediatric patients.
  • To explore the incidence, pathogenesis, diagnostic approaches, treatment, and recovery of anosmia in children.
  • To highlight the significance of anosmia as a potential sole indicator of COVID-19 in pediatric cases.

Main Methods:

  • A systematic review and meta-analysis of existing publications.
  • Statistical processing and generalization of data from multiple sources.
  • Synthesis of findings to understand pediatric COVID-19 anosmia.

Main Results:

  • Literature on pediatric COVID-19 anosmia is less extensive compared to adult studies.
  • Anosmia, often accompanied by ageusia (loss of taste), can be the sole presenting symptom in children.
  • This olfactory dysfunction serves as an early identifier and strong predictor of COVID-19 in pediatric patients.

Conclusions:

  • Further research is needed to differentiate COVID-19-related olfactory dysfunction from other infections like influenza.
  • Investigating anosmia diagnostics in children with autism spectrum and mental disorders is a potential research avenue.
  • Emphasizes the importance of considering anosmia as a key symptom in pediatric COVID-19 diagnostics.
Abstract

Keywords:
ageusiaCOVID-19 infectionanosmiahyposmiaolfaction

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