Related Experiment Video

Updated: Jul 1, 2025

Real-Time Imaging of CCL5-Induced Migration of Periosteal Skeletal Stem Cells in Mice
06:10

Real-Time Imaging of CCL5-Induced Migration of Periosteal Skeletal Stem Cells in Mice

Published on: September 16, 2020

2.3K

Unraveling IGFBP3-mediated m6A modification in fracture healing

Aining Lai1, Junjian Sun2, Zhiyuan Dai3

  • 1Section Ⅱ, Department of Orthopedics, the 72nd Army Hospital of PLA, Huzhou 313000, P. R. China.

Pathology, Research and Practice
|March 3, 2024
PubMed
Abstract

Keywords:
Fracture healingIGFBP3M6A modificationMiR-23a-3pOsteogenic differentiationSMAD5

More Related Videos

Fracture Apparatus Design and Protocol Optimization for Closed-stabilized Fractures in Rodents06:59

Fracture Apparatus Design and Protocol Optimization for Closed-stabilized Fractures in Rodents

Published on: August 14, 2018

13.4K
Sequential In vivo Imaging of Osteogenic Stem/Progenitor Cells During Fracture Repair10:30

Sequential In vivo Imaging of Osteogenic Stem/Progenitor Cells During Fracture Repair

Published on: May 23, 2014

10.5K

Related Concept Videos

TGF - β Signaling Pathway01:16

TGF - β Signaling Pathway

The TGF-β signaling pathway regulates cell growth, differentiation, adhesion, motility, and development. TGF-β ligands that induce TGF-β signaling are synthesized in their latent form. Several proteases or cell surface receptors such as integrins act upon the latent form, releasing the active ligand. There are three types of mammalian TGF-βs: (TGF-β1, TGF-β2, and TGF-β3) that bind as homodimers or heterodimers to TGF-β receptors. The TGF-β receptors...
7.4K
Fractures: Bone Repair01:27

Fractures: Bone Repair

Treatment for a fracture is based on the type of break, the bone affected, and the patient's age.
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the...
3.2K
Intracellular Signaling Affects Focal Adhesions01:17

Intracellular Signaling Affects Focal Adhesions

Integrins act both as extracellular input receivers and as intracellular processing activators. As their name suggests, integrins are entirely integrated into the membrane structure. Their hydrophobic membrane-spanning regions interact with the phospholipid bilayer's hydrophobic region. These membrane receptors provide extracellular attachment sites for effectors like hormones and growth factors. They activate intracellular response cascades when their effectors are bound and active.
Some...
2.7K