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An Image Guided Transapical Mitral Valve Leaflet Puncture Model of Controlled Volume Overload from Mitral Regurgitation in the Rat
Published on: May 19, 2020
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Functional Mitral Regurgitation: Patient Selection and Optimization
Pooja Prasad1, Pranav Chandrashekar2, Harsh Golwala2
1Division of Cardiology, University of California-San Francisco, 505 Parnassus Avenue, Suite M1182, Box 0124, San Francisco, CA 94143, USA.
Interventional Cardiology Clinics
|March 3, 2024
Summary
Functional mitral regurgitation is common in heart failure and impacts symptoms. Transcatheter mitral valve repair is a growing treatment option for selected patients, with expanding indications and devices.
Area of Science:
- Cardiology
- Cardiovascular Surgery
- Medical Devices
Background:
- Functional mitral regurgitation (FMR) is prevalent across heart failure phenotypes.
- FMR significantly contributes to symptom burden and adverse cardiac remodeling.
- Transcatheter mitral valve edge-to-edge repair (TEER) has emerged as a key therapeutic option.
Purpose of the Study:
- To review the role of TEER in managing heart failure patients with FMR.
- To discuss current patient selection criteria and evolving indications for TEER.
- To highlight the expanding landscape of TEER device platforms.
Main Methods:
- Review of current literature and clinical guidelines.
- Analysis of patient selection parameters including heart failure staging and comorbidities.
- Evaluation of anatomical criteria for successful TEER.
Main Results:
- TEER is a valuable addition to the heart failure treatment armamentarium.
- Careful patient selection is crucial for optimal outcomes.
- Indications and available device technologies for TEER are rapidly advancing.
Conclusions:
- TEER offers a minimally invasive approach for selected heart failure patients with FMR.
- Ongoing research and technological advancements are expanding the utility of TEER.
- Personalized patient selection remains paramount for successful FMR management.
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