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Related Concept Videos

Mitral Valve Prolapse II: Assessment and Management01:22

Mitral Valve Prolapse II: Assessment and Management

IntroductionA range of clinical features characterizes Mitral Valve Prolapse (MVP), but it is important to note that many individuals with MVP are asymptomatic and may remain so throughout their lives. For those who do exhibit symptoms, the following are the key clinical features:Palpitations: This is a common symptom where individuals feel an irregular or rapid heartbeat. Palpitations in MVP are often due to arrhythmias such as premature ventricular contractions or supraventricular tachycardia.
Mitral Regurgitation I: Introduction01:20

Mitral Regurgitation I: Introduction

Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
Mitral Regurgitation II: Clinical Features and Diagnostic Tests01:23

Mitral Regurgitation II: Clinical Features and Diagnostic Tests

Mitral regurgitation (MR) is a valvular heart disorder in which the mitral valve fails to close tightly, allowing blood to leak backward into the heart. Understanding the clinical manifestations, assessment, diagnostic findings, and medical management of MR is crucial to effectively managing affected patients.Clinical Manifestations of Mitral RegurgitationMitral regurgitation can be acute or chronic, each presenting differently and requiring different approaches:1. Acute Mitral...
Mitral Regurgitation III: Medical Management01:25

Mitral Regurgitation III: Medical Management

Mitral regurgitation (MR) is characterized by retrograde blood circulation from the left ventricle into the left atrium due to inadequate mitral valve closure. The severity of the condition, symptoms, and underlying cause determine treatment strategies.Monitoring and Pharmacological TreatmentPatients with mild to moderate MR typically do not need immediate intervention but regular monitoring to assess progression and guide treatment. Patients with mild MR should have an echocardiogram every 3-5...
Mitral Regurgitation IV: Nursing Management01:28

Mitral Regurgitation IV: Nursing Management

Mitral regurgitation (MR) is a condition where the mitral valve does not close properly, leading to the backward flow of blood from the left ventricle into the left atrium during systole. This condition can arise from various causes, including rheumatic fever, infective endocarditis, or degenerative valve disease. Effective nursing management is crucial to optimizing patient outcomes and involves comprehensive assessment and targeted interventions.Comprehensive Patient AssessmentA detailed...
Mitral Stenosis III: Medical Management01:26

Mitral Stenosis III: Medical Management

Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...

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Erratum to Author Corrections to: "Canadian Cardiovascular Society 2023 Guidelines on the Fitness to Drive [Canadian Journal of Cardiology, Volume 40, Issue 4 500-523, DOI: 10.1016/j.cjca.2023.09.033]".

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Related Experiment Video

Updated: May 13, 2026

An Image Guided Transapical Mitral Valve Leaflet Puncture Model of Controlled Volume Overload from Mitral Regurgitation in the Rat
07:42

An Image Guided Transapical Mitral Valve Leaflet Puncture Model of Controlled Volume Overload from Mitral Regurgitation in the Rat

Published on: May 19, 2020

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Functional Mitral Regurgitation: Transcatheter Therapy.

Anita W Asgar1

  • 1Structural Heart Program, Montreal Heart Institute, 5000 rue Belanger, Montreal, H1T1C8 Canada.

Interventional Cardiology Clinics
|March 3, 2024
PubMed
Summary

Mitral regurgitation (MR), a common heart valve disease, is increasing. This review covers transcatheter therapies for MR, including targets and current literature findings.

Keywords:
AnnuloplastyMitral regurgitationTranscatheter edge-to-edge repairTranscatheter therapy

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An Image Guided Transapical Mitral Valve Leaflet Puncture Model of Controlled Volume Overload from Mitral Regurgitation in the Rat
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Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Cardiac Surgery

Background:

  • Mitral regurgitation (MR) is a prevalent valvular heart disease with increasing incidence.
  • Transcatheter therapies are emerging as crucial treatment options for MR.
  • Understanding functional MR phenotypes is vital for therapeutic development.

Purpose of the Study:

  • To review the phenotypes of functional or secondary mitral regurgitation.
  • To identify potential therapeutic targets for transcatheter intervention in MR.
  • To summarize the existing literature on transcatheter MR therapies.

Main Methods:

  • Literature review of transcatheter therapies for mitral regurgitation.
  • Analysis of functional MR phenotypes.
  • Evaluation of therapeutic targets and clinical outcomes.

Main Results:

  • Detailed description of functional MR phenotypes.
  • Identification of key targets for transcatheter MR interventions.
  • Synthesis of current data on transcatheter device efficacy and safety.

Conclusions:

  • Transcatheter interventions represent a promising approach for managing mitral regurgitation.
  • Further research and technological advancements are needed to optimize treatment.
  • Personalized therapeutic strategies based on MR phenotypes are essential.