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Updated: Jul 1, 2025

Evaluation of Cardiac Contractility Modulation Therapy in 2D Human Stem Cell-Derived Cardiomyocytes
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[Evaluation of Contractile Function Using Human iPS Cell-derived Cardiomyocytes].

Junko Kurokawa1, Satoshi Shimizu1, Kazuho Sakamoto1

  • 1Department of Bio-informational Pharmacology, Faculty of Pharmaceutical Sciences, University of Shizuoka.

Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan
|March 3, 2024
PubMed
Summary
This summary is machine-generated.

Predicting anti-cancer drug cardiotoxicity using human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) shows promise. Optimizing experimental systems for evaluating hiPSC-CM contractile function is crucial for patient-specific toxicity prediction.

Area of Science:

  • Biomedical Science
  • Cardiology
  • Drug Development
Keywords:
anti-cancer drugcontractile functionheart failureinduced pluripotent stem (iPS) cellmyocyte

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