Evaluation of a new dynamic real-time visualization 25 kHz swept-source optical coherence tomography based biometer

Area of Science:

• Ophthalmology
• Biomedical Engineering
• Medical Imaging

Background:

• Evaluating the accuracy of ophthalmic biometry devices is crucial for refractive surgery outcomes.
• New swept-source optical coherence tomography (SS-OCT) biometers require validation for clinical use.

Purpose of the Study:

• To assess the intraobserver repeatability and interobserver reproducibility of a novel dynamic real-time visualization 25 kHz SS-OCT biometer (ZW-30).
• To compare the measurement agreement of the ZW-30 with a established SS-OCT biometer (IOLMaster 700).

Main Methods:

• Prospective observational study involving 82 healthy eyes.
• Repeated measurements of ocular parameters (AL, CCT, AQD, ACD, LT, Km, AST, J0, J45, CD) using ZW-30 and IOLMaster 700.
• Statistical analysis included within-subject standard deviation, test-retest variability, coefficient of variation, intraclass correlation coefficient, and Bland-Altman plots.

Main Results:

• The ZW-30 demonstrated excellent intraobserver repeatability and interobserver reproducibility with low variability and high ICC values (except for J45).
• Astigmatism magnitude (AST) distribution was similar between the two devices.
• Bland-Altman analysis revealed narrow 95% limits of agreement for all measured ocular parameters.

Conclusions:

• The new dynamic real-time visualization SS-OCT biometer (ZW-30) exhibits high repeatability and reproducibility.
• The ZW-30 provides measurement values comparable to the IOLMaster 700, suggesting interchangeability in clinical practice.