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Updated: Jul 1, 2025

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy
Leg ulcers are indicators of systemic dysfunction in individuals with sickle cell disease
Tiffany A Jackson1, Ashley J Buscetta1, Hasmin C Ramirez1
1Health Disparities Unit, Social and Behavioral Research Branch, National Human Genome Research Institute, Bethesda, Maryland, USA.
None:
Leg ulcers in individuals living with Sickle Cell Disease are evidence of systemic dysfunction. Data from a U.S. study link leg ulcers to wider pulse pressure and markers of chronic hemolysis, inflammation, renal, and liver dysfunction.
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