Study on Oxymatrine-Based Research from 2001 to 2022: A Bibliometric Analysis

Area of Science:

• Pharmacology
• Natural Products
• Bibliometrics

Background:

• Oxymatrine, a quinolizidine alkaloid from Kushen, exhibits diverse therapeutic properties including organ protection, anticancer, and antiviral effects.
• The broad research scope of oxymatrine necessitates a comprehensive overview of its scientific landscape.

Purpose of the Study:

• To conduct a bibliometric analysis of English-written oxymatrine research over the past 22 years.
• To summarize the current status, trends, and key research areas of oxymatrine-based studies.

Main Methods:

• Bibliometric analysis of 267 English-written studies on oxymatrine published over a 22-year period.
• Analysis of publication trends, countries of origin, research fields, and popular topics.

Main Results:

• A steady increase in annual publications with minor fluctuations was observed.
• Research on oxymatrine has expanded globally, with increasing contributions from various countries beyond China.
• Anticancer and anti-inflammatory research emerged as the most prominent fields, indicating significant therapeutic potential.

Conclusions:

• Oxymatrine research is expanding globally, highlighting its therapeutic versatility.
• Continued in-depth investigation is expected to uncover further therapeutic effects and mechanisms.
• Oxymatrine holds potential as a viable therapeutic agent for a wider range of diseases.