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Updated: Jul 1, 2025

An R-Based Landscape Validation of a Competing Risk Model
Published on: September 16, 2022
Risk Evaluation in Occupational Safety and Health Research: Results From a Benchmarking Exercise of Federal and
Sarah A Felknor1, Jessica M K Streit, Angela M Morley
1From the Southwest Center for Occupational and Environmental Health, Department of Environmental and Occupational Health Sciences, The University of Texas Health Science Center at Houston School of Public Health, Houston, TX (S.A.F.); Office of Research Integration, Office of the Director, National Institute for Occupational Safety and Health, Cincinnati, OH (J.M.K.S.); and Office of the Director, National Institute for Occupational Safety and Health, Washington, DC (A.M.M., J.D.P.).
Objective:
Research involving working populations can pose unique ethical and risk evaluation challenges. The purpose of this benchmarking project was to assess how federal agencies and academic institutions approach the interpretation and application of key risk evaluation concepts in research involving workers in their places of employment.
Methods:
Key informant interviews were conducted to ascertain current practices related to assessing soundness of research design, determining risk reasonableness and research relatedness of risks, and evaluating the risk of noninvasive clinical tests in occupational settings.
Results:
There were noteworthy commonalities among the approaches described to review and address critical aspects of risk evaluation for occupational safety and health research involving human participants.
Conclusions:
The insights gleaned may help guide institutional review boards and Human Research Protection Programs as they consider the ethical issues of human subjects research in occupational settings.
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