Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Teeth

Teeth

The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Clinical Utility of Small Extracellular Vesicles as Liquid Biopsy for Oral Mucosal Disease Diagnostics: Emerging Perspectives.

Diagnostics (Basel, Switzerland)·2026

Same author

Cherubism: An African-Focused Review.

Children (Basel, Switzerland)·2026

Same author

Liquid Biopsy in Head and Neck Cancer: Its Present State and Future Role in Africa.

Cells·2023

Same author

Craniofacial, dental, and molecular features of Pyle disease in a South African child.

BDJ open·2022

Same author

Managing vertical dimensions in patients with Amelogenesis Imperfecta: A case report.

Clinical case reports·2022

Same author

Facial imaging to screen for fetal alcohol spectrum disorder: A scoping review.

Alcoholism, clinical and experimental research·2022

Search research articles

Related Experiment Video

Updated: Jul 1, 2025

Oral Biofilm Sampling for Microbiome Analysis in Healthy Children

Oral Biofilm Sampling for Microbiome Analysis in Healthy Children

Published on: December 31, 2017

Bridging the gap between omics research and dental practice.

S Kabbashi¹, I A Roomaney², M Chetty²

¹Department of Craniofacial Biology, Pathology, and Radiology, Faculty of Dentistry, University of Western Cape, Cape Town, South Africa. skabbashi@uwc.ac.za.

|March 4, 2024

Summary

Omics research offers advanced diagnostics and personalized treatments for dentistry. However, integrating these omics approaches into clinical practice faces challenges, especially in low-resource settings, hindering precision oral healthcare adoption.

More Related Videos

Establishing Organoids from Human Tooth as a Powerful Tool Toward Mechanistic Research and Regenerative Therapy

Establishing Organoids from Human Tooth as a Powerful Tool Toward Mechanistic Research and Regenerative Therapy

Published on: April 13, 2022

Digital Hybrid Model Preparation for Virtual Planning of Reconstructive Dentoalveolar Surgical Procedures

Digital Hybrid Model Preparation for Virtual Planning of Reconstructive Dentoalveolar Surgical Procedures

Published on: August 5, 2021

Related Experiment Videos

Last Updated: Jul 1, 2025

Oral Biofilm Sampling for Microbiome Analysis in Healthy Children

Oral Biofilm Sampling for Microbiome Analysis in Healthy Children

Published on: December 31, 2017

Establishing Organoids from Human Tooth as a Powerful Tool Toward Mechanistic Research and Regenerative Therapy

Establishing Organoids from Human Tooth as a Powerful Tool Toward Mechanistic Research and Regenerative Therapy

Published on: April 13, 2022

Digital Hybrid Model Preparation for Virtual Planning of Reconstructive Dentoalveolar Surgical Procedures

Digital Hybrid Model Preparation for Virtual Planning of Reconstructive Dentoalveolar Surgical Procedures

Published on: August 5, 2021

Area of Science:

Dentistry
Genomics
Oral Health
Precision Medicine

Background:

Omics research has rapidly advanced in medicine and dentistry.
Clinical dentistry, particularly in Low- and Middle-Income Countries (LMICs), has lagged in adopting omics-based approaches.
A significant gap exists between omics research breakthroughs and their clinical implementation in dentistry.

Purpose of the Study:

To provide a comprehensive overview of omics integration in dentistry.
To identify challenges and opportunities for translating omics research into clinical practice.
To highlight the limited progress in routine dental practice adoption of omics.

Main Methods:

Conducted a literature review using key databases.
Provided an overview of the history of genomics in dentistry.
Summarized recent omics breakthroughs relevant to oral health practitioners.

Main Results:

Omics research in dentistry has grown significantly but translation to clinical practice remains limited.
Recent omics breakthroughs relevant to oral health are summarized.
The gap between research advancements and clinical implementation is highlighted.

Conclusions:

Omics integration promises enhanced diagnostics, personalized treatments, and preventive care in dentistry.
Challenges like infrastructure, cost, and education hinder widespread adoption of omics in clinical dentistry.
A commitment to transforming dentistry is needed to embrace omics for precision oral healthcare.