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Updated: Jul 1, 2025
Murine Ileocolic Bowel Resection with Primary Anastomosis
Published on: October 29, 2014
Kono-S anastomosis in Crohn's disease: initial experience in pediatric patients
Vojtech Dotlacil1, Tereza Lerchova2, Marketa Lengalova3
1Department of Paediatric Surgery, Second Faculty of Medicine, Charles University and Motol University Hospital, Prague, Charles University, V Uvalu 84, 150 06, Praha 5, Czech Republic. vojtech.dotlacil@fnmotol.cz.
Insights
The Kono-S anastomosis is safe and feasible for children with Crohn's disease (CD) undergoing ileocecal resection (ICR). This surgical technique showed no short- or mid-term complications in pediatric patients, suggesting potential benefits.
Area of Science:
- Pediatric Surgery
- Gastroenterology
- Inflammatory Bowel Disease Research
Background:
- Ileocecal resection (ICR) is common for pediatric Crohn's disease (CD).
- Anastomotic recurrence frequently occurs after ICR in children.
- Limited data exist on anastomosis type's impact on recurrence in pediatric CD.
Purpose of the Study:
- Evaluate the feasibility and safety of the Kono-S anastomosis in pediatric CD patients.
- Assess postoperative complications associated with Kono-S anastomosis in children.
- Investigate the potential of Kono-S anastomosis to reduce recurrence rates in pediatric CD.
Main Methods:
- Retrospective analysis of pediatric CD patients undergoing ICR with Kono-S anastomosis (August 2022 - May 2023).
- Data collected: demographics, clinical features, surgical details, hospitalization, and follow-up (including colonoscopy).
- Complications were graded using the Clavien-Dindo classification.
Main Results:
- Twelve pediatric CD patients were included (58.3% female).
- Median follow-up was 9.5 months with no observed short- or mid-term complications.
- Surgery duration and anastomosis time were recorded, with a median hospitalization of 6 days.
Conclusions:
- Kono-S anastomosis is a safe and feasible surgical option for pediatric Crohn's disease patients.
- The technique demonstrated no postoperative complications in this cohort.
- Findings support further investigation of Kono-S anastomosis for pediatric CD treatment.
Purpose:
Children diagnosed with Crohn's disease (CD) often undergo ileocecal resection (ICR) during childhood. Anastomotic recurrence is a frequent finding following this procedure. Data addressing the effect of the anastomosis type on disease recurrence are scarce in the pediatric population. The Kono-S anastomosis has shown promise in reducing endoscopic, clinical, and surgical recurrence rates in adults. We aimed to report our experience with Kono-S anastomosis in children, focusing on its feasibility and postoperative complications.
Methods:
We retrospectively analyzed pediatric CD patients who underwent ICR with Kono-S anastomosis between August 2022 and May 2023. Data on demographics, clinical characteristics, surgery, hospitalization, and follow-up including colonoscopy were collected. Complications were classified using the Clavien-Dindo classification.
Results:
Twelve patients (7 females, 58.3%) were included. Six (50%) of the patients had the B3 luminal form of the disease (according to Paris classification). Median surgery duration was 174 (interquartile range [IQR] 161-216) minutes. Anastomosis creation took a median of 62 (IQR, 54.5-71) minutes. Median hospitalization length was 6 (IQR 4-7) days. No short- or mid-term complications were observed. Median follow-up duration was 9.5 (IQR 6.8-12) months.
Conclusion:
According to our results, Kono-S anastomosis is safe and feasible in pediatric CD patients, with no observed postoperative complications. These findings support the potential benefit of using Kono-S anastomosis as a treatment approach in children with CD.
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