The influence of burnout on cardiovascular disease: a systematic review and meta-analysis
Awena John1, Jean-Baptiste Bouillon-Minois2, Reza Bagheri3
1Université Clermont Auvergne, CHU Clermont-Ferrand, Occupational Medicine, Clermont-Ferrand, France.
Frontiers in Psychiatry
|March 5, 2024
Summary
Burnout significantly elevates cardiovascular disease risk by 21%, particularly prehypertension. Further research is needed to confirm causality and develop workplace preventive strategies for burnout and cardiovascular health.
Area of Science:
- Public Health
- Occupational Health
- Cardiology
Background:
- Burnout is a recognized public health issue with potential cardiovascular implications.
- Cardiovascular disease (CVD) risk associated with burnout is under investigation.
- This study systematically reviews and meta-analyzes the link between burnout and CVD.
Approach:
- A systematic review and random-effect meta-analysis was conducted.
- Searched major databases (PubMed, PsycINFO, Cochrane, Embase, ScienceDirect) for studies reporting CVD risk post-burnout.
- Analyzed 25 studies (9 in meta-analysis, 26,916 participants), stratifying by CVD type and adjusting for confounders.
Key Points:
- Burnout increased overall CVD risk by 21% (OR=1.21) using adjusted models.
- Significant risk increases observed for prehypertension (85%) and CVD hospitalization (10%).
- No significant risk increase for coronary heart disease or myocardial infarction; results consistent across adjusted and crude analyses.
Conclusions:
- Burnout appears to elevate cardiovascular disease risk, though causality is limited by study design.
- Further research into the pathophysiology of burnout-related CVD risk is warranted.
- Findings suggest potential for developing workplace preventive strategies targeting burnout and cardiovascular health.
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