Related Experiment Video
Updated: Jul 1, 2025

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
Published on: September 20, 2018
Aspergillosis Causing Orbital Subperiosteal Abscess in an Immunocompetent Child: A Rare Presentation
Stuti Chowdhary1, Anjali Mary Jibi2, Winsley Rose3
1Department of Otorhinolaryngology, Christian Medical College, Vellore, 632004 India.
Abstract:
Orbital abscesses are primarily seen in children as complication of ethmoid bacterial sinusitis. We report a case of invasive aspergillosis causing orbital abscess in an immunocompetent child which resolved with surgery followed by antifungal therapy. This case highlights need for histopathological, and microbiological examination, including fungal culture in such cases.
Insights
Orbital abscesses, often from bacterial sinusitis in children, can rarely be caused by invasive aspergillosis. Prompt diagnosis via fungal culture and treatment with surgery and antifungals are crucial for recovery.
Area of Science:
- Ophthalmology
- Pediatrics
- Infectious Diseases
- Mycology
Background:
- Orbital abscesses are typically a complication of bacterial sinusitis in pediatric patients.
- Invasive fungal infections, such as aspergillosis, are less common causes of orbital abscesses, particularly in immunocompetent children.
Purpose of the Study:
- To report a rare case of invasive aspergillosis presenting as an orbital abscess in an immunocompetent child.
- To emphasize the diagnostic and therapeutic approach for fungal orbital abscesses.
Main Methods:
- Case report detailing clinical presentation, diagnostic workup, and treatment.
- Histopathological and microbiological examination, including fungal culture, were performed.
- Surgical intervention followed by antifungal therapy was administered.
Main Results:
- A diagnosis of invasive aspergillosis was confirmed.
- The orbital abscess resolved successfully following surgical debridement and systemic antifungal treatment.
- The importance of considering fungal etiology in orbital infections was underscored.
Conclusions:
- Invasive aspergillosis can cause orbital abscesses even in immunocompetent children.
- Histopathological and microbiological evaluations, including fungal cultures, are essential for accurate diagnosis.
- Multimodal treatment involving surgery and antifungal therapy is effective.
Related Concept Videos
Immunodeficiency Diseases
There are three main causes of immunodeficiency...
Development of Immunocompetence
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
Skin Diseases and Disorders
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...

