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Related Concept Videos

Gastroesophageal Reflux Disease II: Clinical Features and Management01:29

Gastroesophageal Reflux Disease II: Clinical Features and Management

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Gastroesophageal reflux disease, or GERD, is a persistent medical condition that affects many individuals worldwide. Its clinical manifestations can vary greatly, making diagnosis and management challenging for healthcare professionals. The following is a comprehensive overview of the clinical manifestations, assessment, and management strategies for GERD.
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
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Barrett Esophagus-II: Clinical Manifestations and Management01:21

Barrett Esophagus-II: Clinical Manifestations and Management

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Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
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Assessment of the Cardiovascular System II: Inspection01:29

Assessment of the Cardiovascular System II: Inspection

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Inspection is the initial step in assessing the cardiovascular system. It involves a detailed visual examination that provides crucial information about a patient's circulatory and cardiac health. This systematic process, conducted from head to toe, helps identify signs of cardiovascular conditions by observing physical appearance, skin and mucous membranes, jugular and carotid pulsations, chest symmetry, and the condition of the extremities.
Head and Neck
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Esophageal Strictures-I: Introduction01:30

Esophageal Strictures-I: Introduction

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Esophageal strictures involve abnormal narrowing or tightening of the esophagus. They vary in length and severity, ranging from mild constriction to complete obstruction, and are classified as benign (noncancerous) or malignant (cancerous).
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
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Esophageal Strictures-II: Clinical Features and Management01:26

Esophageal Strictures-II: Clinical Features and Management

70
Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
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Disorders of the Skeletal Muscle01:28

Disorders of the Skeletal Muscle

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The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
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A Googly in the Neck-Castleman Disease.

Ritu K Sheth1, Purnima Kumar1, Athira Vishnurag1

  • 1Department of ENT, Seth V.C Gandhi & M. A. Vora Municipal General Hospital, Mumbai, India.

Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India
|March 5, 2024
PubMed
Summary

Castleman disease (CD) is a rare lymphoproliferative disorder causing enlarged lymph nodes and inflammation. Surgical treatment led to a full recovery in a young patient, highlighting effective management for this condition.

Keywords:
Neck massPaediatric Castleman diseaseUnicentric CD

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Area of Science:

  • Hematology
  • Oncology
  • Immunology

Background:

  • Lymphoproliferative disorders involve uncontrolled lymphocyte production.
  • Castleman disease (CD) is a rare disorder characterized by enlarged lymph nodes and systemic inflammatory symptoms.
  • CD presents with diverse clinical and laboratory abnormalities.

Purpose of the Study:

  • To present a case study of a young patient diagnosed with Castleman disease.
  • To illustrate the diagnostic and treatment pathway for Castleman disease.
  • To emphasize the potential for successful surgical management of CD.

Main Methods:

  • Diagnosis was confirmed through tissue biopsy after excluding other pathologies.
  • The patient underwent surgical intervention for the condition.
  • Post-operative follow-up confirmed disease eradication.

Main Results:

  • A young female patient was diagnosed with Castleman disease.
  • Surgical treatment was successfully performed.
  • The patient achieved a disease-free status post-surgery.

Conclusions:

  • Castleman disease requires accurate diagnosis through methods like tissue biopsy.
  • Surgical resection can be an effective primary treatment for localized CD.
  • Early diagnosis and intervention lead to favorable outcomes in young patients with Castleman disease.