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A Googly in the Neck-Castleman Disease
Ritu K Sheth1, Purnima Kumar1, Athira Vishnurag1
1Department of ENT, Seth V.C Gandhi & M. A. Vora Municipal General Hospital, Mumbai, India.
Insights
Castleman disease (CD) is a rare lymphoproliferative disorder causing enlarged lymph nodes and inflammation. Surgical treatment led to a full recovery in a young patient, highlighting effective management for this condition.
Area of Science:
- Hematology
- Oncology
- Immunology
Background:
- Lymphoproliferative disorders involve uncontrolled lymphocyte production.
- Castleman disease (CD) is a rare disorder characterized by enlarged lymph nodes and systemic inflammatory symptoms.
- CD presents with diverse clinical and laboratory abnormalities.
Purpose of the Study:
- To present a case study of a young patient diagnosed with Castleman disease.
- To illustrate the diagnostic and treatment pathway for Castleman disease.
- To emphasize the potential for successful surgical management of CD.
Main Methods:
- Diagnosis was confirmed through tissue biopsy after excluding other pathologies.
- The patient underwent surgical intervention for the condition.
- Post-operative follow-up confirmed disease eradication.
Main Results:
- A young female patient was diagnosed with Castleman disease.
- Surgical treatment was successfully performed.
- The patient achieved a disease-free status post-surgery.
Conclusions:
- Castleman disease requires accurate diagnosis through methods like tissue biopsy.
- Surgical resection can be an effective primary treatment for localized CD.
- Early diagnosis and intervention lead to favorable outcomes in young patients with Castleman disease.
Abstract:
Lymphoproliferative disorders comprise of a group of heterogenous diseases characterised by uncontrolled production of lymphocytes.Castleman disease (CD) is one such disease and comprises of a group of rare disorders that involve enlarged lymph nodes and a broad range of inflammatory symptoms and laboratory abnormalities [1]. We came across young girl who presented to us in the out patient department with this disease After ruling out other pathologies and confirming the diagnosis by doing a tissue biopsy the girl was treated surgically and is disease free till date.
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