Related Experiment Video
Updated: Jul 1, 2025

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
Published on: June 9, 2023
A Googly in the Neck-Castleman Disease
Ritu K Sheth1, Purnima Kumar1, Athira Vishnurag1
1Department of ENT, Seth V.C Gandhi & M. A. Vora Municipal General Hospital, Mumbai, India.
Castleman disease (CD) is a rare lymphoproliferative disorder causing enlarged lymph nodes and inflammation. Surgical treatment led to a full recovery in a young patient, highlighting effective management for this condition.
Area of Science:
- Hematology
- Oncology
- Immunology
Background:
- Lymphoproliferative disorders involve uncontrolled lymphocyte production.
- Castleman disease (CD) is a rare disorder characterized by enlarged lymph nodes and systemic inflammatory symptoms.
- CD presents with diverse clinical and laboratory abnormalities.
Purpose of the Study:
- To present a case study of a young patient diagnosed with Castleman disease.
- To illustrate the diagnostic and treatment pathway for Castleman disease.
- To emphasize the potential for successful surgical management of CD.
Main Methods:
- Diagnosis was confirmed through tissue biopsy after excluding other pathologies.
- The patient underwent surgical intervention for the condition.
- Post-operative follow-up confirmed disease eradication.
Main Results:
- A young female patient was diagnosed with Castleman disease.
- Surgical treatment was successfully performed.
- The patient achieved a disease-free status post-surgery.
Conclusions:
- Castleman disease requires accurate diagnosis through methods like tissue biopsy.
- Surgical resection can be an effective primary treatment for localized CD.
- Early diagnosis and intervention lead to favorable outcomes in young patients with Castleman disease.
Related Concept Videos
Gastroesophageal Reflux Disease II: Clinical Features and Management
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
Barrett Esophagus-II: Clinical Manifestations and Management
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
Assessment of the Cardiovascular System II: Inspection
Head and Neck
Esophageal Strictures-I: Introduction
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
Esophageal Strictures-II: Clinical Features and Management
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
Disorders of the Skeletal Muscle
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...

