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Measuring G-protein-coupled Receptor Signaling via Radio-labeled GTP Binding
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Beyond the Nucleus: Plastic Chemicals Activate G Protein-Coupled Receptors

Molly McPartland1, Sarah Stevens1, Zdenka Bartosova1

  • 1Department of Biology, Norwegian University of Science and Technology (NTNU), Trondheim 7491, Norway.

Environmental Science & Technology
|March 5, 2024
PubMed
Summary

Plastic chemicals disrupt cell signaling by targeting G protein-coupled receptors (GPCRs), particularly adenosine receptor 1 (ADORA1) and melatonin receptor 1 (MTNR1A), impacting circadian and metabolic processes.

Keywords:
GPCRsPRESTO-Tangocell surface receptorendocrine disrupting chemicalsfood packagingplasticsscreensignaling disruption

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