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Updated: Jul 1, 2025

Preparation of Myeloid Derived Suppressor Cells MDSC from Naive and Pancreatic Tumor-bearing Mice using Flow Cytometry and Automated Magnetic Activated Cell Sorting AutoMACS
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Progress in research on the role played by myeloid-derived suppressor cells in liver diseases

Qianqian Sun1, Heng Dai1, Siliang Wang2

  • 1Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.

Scandinavian Journal of Immunology
|March 5, 2024
PubMed

Myeloid-derived suppressor cells (MDSCs) refer to a group of immature myeloid cells with potent immunosuppressive capacity upon activation by pathological conditions. Because of their potent immunosuppressive ability, MDSCs have garnered extensive attention in the past few years in the fields of oncology, infection, chronic inflammation and autoimmune diseases. Research on MDSCs in liver diseases has gradually increased, and their potential therapeutic roles will be further explored. This review presents a summary of the involvement and the role played by MDSCs in liver diseases, thus identifying their potential targets for the treatment of liver diseases and providing new directions for liver disease-related research.

Keywords:
immunosuppressionimmunotherapyliver diseasesmyeloid‐derived suppressor cells

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