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Related Concept Videos

Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

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Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
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Asthma-III: Symptoms and Complications01:24

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Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
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Asthma: Pathogenesis and Management01:20

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Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
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Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs01:25

Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs

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Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
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Drugs Used in Lower Respiratory Disorders: Overview01:17

Drugs Used in Lower Respiratory Disorders: Overview

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Lower respiratory tract disorders present challenges that often require skilled and nuanced approaches for effective management. Common ailments, such as asthma and chronic obstructive pulmonary disease (COPD), have prompted the development of intricate treatment strategies involving bronchodilators and anti-inflammatory drugs, each tailored to ease breathing and revitalize the lungs.
Bronchodilators, the first step of respiration enhancement, come in various forms, each with its own mechanism...
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Asthma-IV: Diagnostic and Management01:30

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The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
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Related Experiment Video

Updated: Jul 1, 2025

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
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Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

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Remission in asthma.

Marek Lommatzsch1

  • 1Department of Pneumology, University of Rostock, Rostock, Germany.

Current Opinion in Pulmonary Medicine
|March 5, 2024
PubMed
Summary
This summary is machine-generated.

Asthma treatment goals are shifting from disease control to remission, defined by symptom absence, no steroid use, and minimal symptoms for one year. Achieving remission requires precise patient phenotyping and biomarker measurement for long-term prevention.

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Area of Science:

  • Pulmonology
  • Allergy and Immunology

Background:

  • Asthma management historically focused on stepwise control, adding medications to achieve the best possible symptom control.
  • Recent advancements in anti-inflammatory therapies have prompted a paradigm shift towards long-term disease modification and prevention.

Approach:

  • Review of current asthma guidelines and emerging concepts of remission.
  • Analysis of the evolving definition of asthma remission and its clinical implications.
  • Discussion of the role of phenotyping and biomarkers in achieving remission.

Key Points:

  • Asthma remission is now a treatment goal in several national guidelines, signifying a move from symptom control to prevention.
  • Current consensus defines remission by at least one year of no exacerbations, no systemic corticosteroid use, and minimal asthma symptoms.
  • Precise patient phenotyping, including biomarker analysis, is crucial for achieving individual clinical remission.

Conclusions:

  • The inclusion of remission as an asthma treatment goal reflects a significant shift in therapeutic strategy.
  • A universally accepted, evidence-based definition of asthma remission is needed for clinical practice.
  • Future efforts should focus on establishing international consensus and refining phenotyping approaches for optimal asthma remission.