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Related Experiment Video

Updated: Jul 1, 2025

Estimating Vestibular Perceptual Thresholds Using a Six-Degree-Of-Freedom Motion Platform

Estimating Vestibular Perceptual Thresholds Using a Six-Degree-Of-Freedom Motion Platform

Published on: August 4, 2022

Visual and vestibular motion perception in persistent postural-perceptual dizziness (PPPD).

Renana Storm¹, Janina Krause^1,2, Smila-Karlotta Blüm^1,2

¹Department of Neurology, University Hospital Schleswig-Holstein, University of Lübeck, Campus Lübeck, Ratzeburger Allee 160, 23538, Lübeck, Germany.

Journal of Neurology

|March 5, 2024

Summary

Persistent postural-perceptual dizziness (PPPD) involves abnormal sensory scaling. Patients with PPPD show altered visual motion perception and vestibular responses, suggesting a unique sensory processing issue.

Keywords:

Functional disorder Motion perception PPPD Persistent postural-perceptual dizziness Vestibular

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Last Updated: Jul 1, 2025

Estimating Vestibular Perceptual Thresholds Using a Six-Degree-Of-Freedom Motion Platform

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Published on: August 4, 2022

Assessment of Static Graviceptive Perception in the Roll-Plane using the Subjective Visual Vertical Paradigm

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Published on: April 28, 2020

Using Unidirectional Rotations to Improve Vestibular System Asymmetry in Patients with Vestibular Dysfunction

Using Unidirectional Rotations to Improve Vestibular System Asymmetry in Patients with Vestibular Dysfunction

Published on: August 30, 2019

Area of Science:

Neuroscience
Vestibular System
Sensory Perception

Background:

Persistent postural-perceptual dizziness (PPPD) is a chronic condition characterized by perceived unsteadiness.
Symptoms worsen in visually complex environments, and visual dependence/motion sensitivity are known predictors.
The underlying pathophysiology of PPPD remains largely unknown.

Purpose of the Study:

To investigate a hypothesized abnormal sensory-perceptual scaling mechanism in PPPD.
To compare visual and vestibular perceptual thresholds between PPPD patients and healthy controls (HC).

Main Methods:

Assessed visual motion coherence thresholds using random dot kinetograms.
Evaluated vestibular egomotion perception thresholds via galvanic vestibular stimulation (GVS) and passive chair rotation.
Compared patient and HC performance on motion and sham (no-motion) stimulus trials.

Main Results:

PPPD patients had higher visual motion perception thresholds than HC.
Patients showed a lower GVS perception threshold but similar egomotion perception during chair rotation compared to HC.
In PPPD patients, correct perception in no-motion trials increased with rotatory egomotion thresholds, unlike in HC.

Conclusions:

Findings suggest an abnormal sensory-perceptual scaling in PPPD, particularly in visual motion processing and vestibular-visual integration.
Altered sensory scaling may contribute to the chronic dizziness and unsteadiness experienced by PPPD patients.
Vestibular perception thresholds may predict false sensory assignments in PPPD, highlighting a potential diagnostic marker.