Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Tumor Progression02:07

Tumor Progression

6.2K
Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
6.2K
The Aorta01:14

The Aorta

4.2K
The aorta is the largest artery in the human body. It originates from the left ventricle of the heart and extends down to the abdomen, where it splits into two smaller arteries. Structurally, it can be divided into four main parts: the ascending aorta, the aortic arch, the thoracic aorta, and the abdominal aorta.
The average diameter of the aorta is approximately 2-3 cm, but the size can vary depending on the section of the aorta and the individual's age, sex, and body size. The aorta is...
4.2K
Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

589
Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
589
Aneurysm III: Interprofessional Care01:26

Aneurysm III: Interprofessional Care

478
Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
478

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Third-generation cephalosporin-induced L-form transition in <i>Shigella sonnei</i> reveals a virulence-survival trade-off underlying persistent infection.

Microbiology spectrum·2026
Same author

Real world experience with cyclin dependent kinase inhibitors in metastatic breast cancer in India.

PloS one·2026
Same author

Hybrid versus endocardial ablation for persistent atrial fibrillation: a systematic review and Bayesian meta-analysis.

Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing·2026
Same author

Safety, immunogenicity and preliminary protective efficacy of a bivalent bacterial ghost vaccine against typhoidal Salmonella in rabbits: a pilot study.

Vaccine·2025
Same author

Clinical and Genotypic Insights into Turner Syndrome: Emphasis on Cardiovascular Abnormalities.

Journal of the ASEAN Federation of Endocrine Societies·2025
Same author

Clinical Efficacy and Safety of Gemcitabine-Cisplatin Combination in Metastatic Gallbladder Cancer: A Prospective Study from North India.

Journal of gastrointestinal cancer·2025

Related Experiment Video

Updated: Apr 30, 2026

Arterial Pouch Microsurgical Bifurcation Aneurysm Model in the Rabbit
06:11

Arterial Pouch Microsurgical Bifurcation Aneurysm Model in the Rabbit

Published on: May 14, 2020

2.4K

Giant Aneurysms: Not So Giant in Behavior.

Parthasarathi Datta1, Shuvankar Mukherjee2, Anindya Mukherjee3

  • 1Department of Neurosurgery, Nil Ratan Sircar Medical College, Kolkata, West Bengal, India.

Neurology India
|March 5, 2024
PubMed
Summary
This summary is machine-generated.

Giant intracranial aneurysms (GIAs) have a similar intraoperative rupture rate (IRR) to smaller aneurysms. This study found no statistically significant difference in IRR, challenging previous assumptions about GIA surgical risks.

More Related Videos

Creation of Two Saccular Elastase-Digested Aneurysms with Different Hemodynamics in One Rabbit
07:04

Creation of Two Saccular Elastase-Digested Aneurysms with Different Hemodynamics in One Rabbit

Published on: April 15, 2021

2.1K
Microsurgical Creation of Giant Bifurcation Aneurysms in Rabbits for the Evaluation of Endovascular Devices
07:21

Microsurgical Creation of Giant Bifurcation Aneurysms in Rabbits for the Evaluation of Endovascular Devices

Published on: September 8, 2023

723

Related Experiment Videos

Last Updated: Apr 30, 2026

Arterial Pouch Microsurgical Bifurcation Aneurysm Model in the Rabbit
06:11

Arterial Pouch Microsurgical Bifurcation Aneurysm Model in the Rabbit

Published on: May 14, 2020

2.4K
Creation of Two Saccular Elastase-Digested Aneurysms with Different Hemodynamics in One Rabbit
07:04

Creation of Two Saccular Elastase-Digested Aneurysms with Different Hemodynamics in One Rabbit

Published on: April 15, 2021

2.1K
Microsurgical Creation of Giant Bifurcation Aneurysms in Rabbits for the Evaluation of Endovascular Devices
07:21

Microsurgical Creation of Giant Bifurcation Aneurysms in Rabbits for the Evaluation of Endovascular Devices

Published on: September 8, 2023

723

Area of Science:

  • Neurosurgery
  • Vascular Neurology
  • Medical Statistics

Background:

  • Giant intracranial aneurysms (GIAs) present unique surgical challenges.
  • GIAs have a higher annual rupture rate (6%) compared to small aneurysms (1-3%).

Purpose of the Study:

  • To compare the intraoperative rupture rate (IRR) of GIAs with that of small aneurysms.
  • To determine if GIAs pose a statistically higher risk of rupture during surgical procedures.

Main Methods:

  • A retrospective comparison of IRR was conducted for 7 GIAs and 45 small aneurysms.
  • All surgical procedures were performed by the same surgical team over a 10-year period.
  • Statistical analysis, including Z-test, was used to compare rupture rates.

Main Results:

  • The IRR for GIAs was found to be statistically similar to that of small aneurysms (Z = 0.68, P = 0.49).
  • Factors contributing to the similar IRR include intraaneurysmal thrombus, fibrin deposition, and thrombus-occluded aneurysm necks.

Conclusions:

  • The intraoperative rupture rate of giant intracranial aneurysms is not significantly different from that of small aneurysms.
  • Surgical management of GIAs may not inherently carry a higher intraoperative rupture risk than smaller aneurysms.