Conduction System Pacing in Pediatrics and Congenital Heart Disease: A Case Report and Literature Review

Michael Scott1, Joseph S Needleman2, Adam C Kean1

  • 1Division of Pediatric Cardiology, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA.

Insights

Left bundle branch pacing (LBBP) offers a safe alternative to right ventricular pacing for preventing cardiomyopathy. This study highlights LBBP

Area of Science:

  • Cardiology
  • Electrophysiology
  • Pediatric Heart Disease

Background:

  • Conduction system pacing, including His bundle pacing (HBP) and left bundle branch pacing (LBBP), is an alternative to right ventricular (RV) pacing.
  • This pacing modality aims to prevent pacemaker-associated cardiomyopathy.
  • LBBP has demonstrated safety and efficacy in pediatric populations in prior small studies.

Purpose of the Study:

  • To present a case of successful left bundle branch pacing (LBBP) in a pediatric patient with congenital heart disease.
  • To evaluate the transition from RV pacing to LBBP for improving left ventricular function.
  • To provide a foundation for reviewing LBBP in pediatrics and congenital heart disease.

Main Methods:

  • Case report detailing a patient with congenital atrioventricular block and cardiomyopathy post-ventricular septal defect repair.
  • Transition of pacing from a right ventricular (RV) epicardial system to a left bundle branch pacing (LBBP) system.
  • Assessment of left ventricular function post-pacing system change.

Main Results:

  • The patient experienced improvement in left ventricular function after transitioning to LBBP.
  • This suggests LBBP can be effective in pediatric patients with specific cardiac conditions.
  • The case supports LBBP as a viable alternative to RV pacing in complex pediatric cases.

Conclusions:

  • Left bundle branch pacing (LBBP) is a safe and effective alternative to right ventricular (RV) pacing in pediatric patients.
  • LBBP can lead to significant improvement in left ventricular function in patients with congenital heart disease and cardiomyopathy.
  • Further research and case reviews are warranted to establish LBBP's role in pediatric and congenital heart disease management.

Related Concept Videos

Conduction System of the Heart01:19

Conduction System of the Heart

Autorhythmicity is a term that refers to the heart's inherent ability to generate electrical signals and instigate muscle contractions. This self-regulating conduction system within the heart consists of two key components: the pacemaker cells and specialized conducting cells.
The pacemaker cells are located in two primary nodes: the sinoatrial (SA) node and the atrioventricular (AV) node. The SA node pacemaker cells can autonomously depolarize, triggering an action potential that leads to the...
6.7K
Electrophysiology of Normal Cardiac Rhythm01:19

Electrophysiology of Normal Cardiac Rhythm

The normal cardiac rhythm is a synchronized electrical activity that facilitates the regular and coordinated contraction of the heart muscle. This process is essential for efficient blood circulation throughout the body. The fundamental elements involved in establishing and maintaining this rhythm include the unique electrical properties of cardiac muscle cells, the sinoatrial (SA) node's pacemaker function, the specialized conducting system, and the ionic mechanisms underlying each phase...
4.2K
Pulse rhythm01:30

Pulse rhythm

Pulse rhythm refers to the pattern of pulsations within specific intervals, offering valuable insights into the regularity or irregularity of the heart's beats as observed through the pattern of pulsation within specific intervals. A regular pulse exhibits a consistent heart rate with uniform waveforms and pulsation force, variations of which can be classified as normal, weak, or bounding.
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac...
797
Mechanism of Cardiac Arrhythmias01:28

Mechanism of Cardiac Arrhythmias

Arrhythmias are irregular heart rhythms occurring when the heart's electrical impulses become abnormal. These disturbances can lead to various symptoms, depending on their severity and the underlying cause. Some common factors contributing to arrhythmias include hypoxia, ischemia, electrolyte imbalances, excessive catecholamine exposure, drug toxicity, and muscle overstretching. Arrhythmias can be classified into two main types based on the rate and site of origin of abnormal heart rhythms.
919
Disturbances in Heart Rhythm01:28

Disturbances in Heart Rhythm

Arrhythmia or dysrhythmia refers to an abnormal heart rhythm caused by a defect in the heart's conduction system. It can cause the heart to beat irregularly, too quickly, or too slowly, leading to symptoms like chest pain, shortness of breath, and fainting. Factors such as stress, caffeine, alcohol, nicotine, cocaine, certain drugs, congenital defects, diseases, and electrolyte abnormalities can trigger arrhythmias.
Arrhythmias are categorized by their speed, rhythm, and origin. A slow...
952
The Cardiac Cycle01:13

The Cardiac Cycle

The heart beats rhythmically in a sequence called the cardiac cycle—a rapid coordination of contraction (systole) and relaxation (diastole).
The Process
Electrical signals—sent from the sinoatrial (SA) node in the right atrial wall to the atrioventricular (AV) node between the right atrium and right ventricle—cause both atria to simultaneously contract. When the signal reaches the AV node, it pauses for approximately a tenth of a second, allowing the atria to contract and...
88.0K