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Is there any association between celiac disease, myelodysplastic symdrome and primary sclerosing cholangitis?: A rare
Suaad Hamsho1, Moudar Al Hariri2, Bilal Sleiay3
1Rheumatology Department, Faculty of Medicine Damascus University Damascus Syria.
Insights
Celiac disease (CD) can present solely with hematological abnormalities, such as myelodysplastic syndrome. Investigating CD in patients with unexplained blood disorders is crucial for accurate diagnosis and management.
Area of Science:
- Gastroenterology
- Hematology
- Immunology
Background:
- Celiac disease (CD) is an autoimmune disorder with diverse clinical manifestations.
- Hematological abnormalities are frequent, sometimes being the sole indicator of CD.
- Unexplained hematological findings warrant a high suspicion for CD.
Abstract:
Celiac disease (CD) is an autoimmune disease characterized by a specific serological and histological profile. Hematological findings are one of the most common presentations and can sometimes be the only manifestation of the disease. In patients with unexplained isolated hematological abnormalities, a high index of suspicion for CD is necessary. A 33-year-old woman was admitted to the Department of Gastroenterology and Hepatology because of abdominal pain and fatigue. She was diagnosed with myelodysplastic syndrome. After many investigations, it is explained that she has CD. It is important to consider myelodysplastic syndrome as a hematological manifestation of CD. All patients with myelodysplasia should be investigated for CD and related conditions such as primary sclerosing cholangitis.
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