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Updated: Jul 1, 2025

Author Spotlight: Evaluation of Protein-Condensate Dynamics in Live Human Cells
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Author Spotlight: Evaluation of Protein-Condensate Dynamics in Live Human Cells

Published on: January 5, 2024

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Specific protein-RNA interactions are mostly preserved in biomolecular condensates

Tebbe de Vries1, Mihajlo Novakovic1, Yinan Ni1

  • 1Department of Biology, Institute of Biochemistry, ETH Zurich, Zurich, Switzerland.

Science Advances
|March 6, 2024
PubMed
Summary

We developed a new method, LLPS-CLIR-MS, to study how RNA binding proteins (RBPs) and RNAs interact within biomolecular condensates. This technique reveals how these interactions change during phase separation.

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