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Updated: Jul 1, 2025
Microfluidic Imaging Flow Cytometry by Asymmetric-detection Time-stretch Optical Microscopy ATOM
Published on: June 28, 2017
Dynamic contrast optical coherence tomography (DyC-OCT) for label-free live cell imaging
Chao Ren1,2, Senyue Hao3, Fei Wang1
1Department of Biomedical Engineering, Washington University in St Louis, St. Louis, MO, USA.
Abstract:
Dynamic contrast optical coherence tomography (DyC-OCT), an emerging imaging method, utilizes fluctuation patterns in OCT signals to enhance contrast, thereby enabling non-invasive label-free volumetric live cell imaging. In this mini review, we explain the core concepts behind DyC-OCT image formation and its system configurations, serving as practical guidance for future DyC-OCT users. Subsequently, we explore its applications in delivering high-quality, contrast-enhanced images of cellular morphology, as well as in monitoring changes in cellular activity/viability assay experiments.
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