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Hyperbaric oxygen effectively addresses the pathophysiology of long COVID: clinical review

Alan A Katz1,2, Sandra Wainwright3, Matthew P Kelly4

  • 1Hyperbaric Medical Solutions, New York, NY, United States.

Frontiers in Medicine
|March 7, 2024
PubMed

Insights

Long COVID, affecting millions with persistent symptoms, shows significant improvement with Hyperbaric Oxygen Therapy (HBO). Research indicates HBO is a safe and promising adjunctive treatment for post-COVID-19 syndrome.

Area of Science:

  • Pulmonology
  • Infectious Diseases
  • Nephrology

Background:

  • Long COVID is defined as persistent symptoms lasting over 3 months post-SARS-CoV-2 infection, impacting millions globally.
  • Patients experience ongoing symptoms for over 12 weeks without alternative diagnoses, leading to reduced quality of life.
  • Currently, no definitive therapeutics effectively treat the underlying pathophysiology of long COVID.

Purpose of the Study:

  • To evaluate the efficacy of Hyperbaric Oxygen Therapy (HBO) as a treatment for long COVID.
  • To review existing literature on the use of HBO for managing post-COVID-19 syndrome.

Main Methods:

  • A comprehensive literature search was conducted using PubMed and Google Scholar.
  • Articles published between November 2021 and January 2024, using keywords "long covid" and "hyperbaric oxygen," were reviewed.
  • Included studies encompassed case series and randomized controlled trials.

Main Results:

  • Published studies indicate that Hyperbaric Oxygen Therapy (HBO) significantly improves outcomes for patients with long COVID.
  • Review of case series and randomized trials demonstrates positive effects of HBO on long COVID symptoms.

Conclusions:

  • A significant patient cohort suffers from long COVID (post-COVID-19 syndrome) with limited treatment options.
  • Hyperbaric Oxygen Therapy (HBO) is a safe treatment modality that may benefit this population.
  • Further research into HBO as an adjunctive treatment for long COVID is warranted.
Abstract

Keywords:
HBOhyperbarichyperbaric oxygen therapylong COVIDpost-COVID-19 syndrome

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